Catalog No.
RHB98205
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
70 kDa lamin, Prelamin-A/C, Renal carcinoma antigen NY-REN-32, LMNA, LMN1, Lamin A, Lamin C
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P02545
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2X94
Detection of Nuclear Blebbing and DNA Leakage in Mammalian Cells by Immunofluorescence., PMID:39895614
SMAP3-ID for Identification of Endogenous Protein-Protein Interactions Reveals Regulation of Mitochondrial Activity by Lamins., PMID:39886595
Mineral Stress Drives Loss of Heterochromatin: An Early Harbinger of Vascular Inflammaging and Calcification., PMID:39840455
Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature., PMID:39422121
Atypical structure of the nuclear membrane, distribution of nuclear pores and lamin B1 in spermatozoa of patients with complete and partial globozoospermia., PMID:39045326
Hutchinson-Gilford progeria syndrome mice display accelerated arterial thrombus formation and increased platelet reactivity., PMID:39032390
Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite., PMID:38821061
Vesicular translocation of PARP-1 to cytoplasm causes ADP-ribosylation and disassembly of vimentin filaments during microglia activation induced by LPS., PMID:38590714
High-throughput Second-generation Sequencing Technology Assisted Diagnosis of Familial Partial Lipodystrophy (Type 2 Kobberling-Dunnigan Syndrome): A Case Report., PMID:37231758
The lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding., PMID:36809122
Glycan analysis of Lamin A/C protein at G2/M and S phases of the cell cycle., PMID:36180658
Podocytes are lost from glomeruli before completing apoptosis., PMID:36049065
A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia., PMID:36016656
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts., PMID:35008948
Super-Resolution Imaging of the A- and B-Type Lamin Networks: A Comparative Study of Different Fluorescence Labeling Procedures., PMID:34638534
[Towards gene therapy for Progeria ?]., PMID:33908864
The Long Linker Region of Telomere-Binding Protein TRF2 Is Responsible for Interactions with Lamins., PMID:33804854
Novel and Efficient Protocol for DNA Coating-Based Identification of DNA-Protein Interaction by Antibody-Mediated Immunodetection., PMID:33649719
LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior., PMID:33605210
Lamin-Related Congenital Muscular Dystrophy Alters Mechanical Signaling and Skeletal Muscle Growth., PMID:33396724
Separation of Coiled-Coil Structures in Lamin A/C Is Required for the Elongation of the Filament., PMID:33396475
Comprehensive analysis of ALK, ROS1 and RET rearrangements in locally advanced rectal cancer., PMID:33168793
Lamin A/C and the Immune System: One Intermediate Filament, Many Faces., PMID:32854281
Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency., PMID:32479501
Impact of injection frequency on 5-year real-world visual acuity outcomes of aflibercept therapy for neovascular age-related macular degeneration., PMID:32265509
Profiling non-HLA antibody responses in antibody-mediated rejection following heart transplantation., PMID:32190967
Multiplexed single-cell morphometry for hematopathology diagnostics., PMID:32161403
c-Fos separation from Lamin A/C by GDF15 promotes colon cancer invasion and metastasis in inflammatory microenvironment., PMID:31613004
The macrophage checkpoint CD47 : SIRPα for recognition of 'self' cells: from clinical trials of blocking antibodies to mechanobiological fundamentals., PMID:31431181
Constitutional abnormality of nuclear membrane proteins in small cell lung carcinoma., PMID:31201505
Quantification of the Lamin A/C Transcript Variants in Cancer Cell Lines by Targeted Absolute Quantitative Proteomics and Correlation with mRNA Expression., PMID:30999625
Detection and quantification of VEGFR-1 in the nuclei of tumor cells by a new flow cytometry-based method., PMID:30985194
Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients., PMID:30871242
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society., PMID:30586772
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society., PMID:30586771
Expression of lamin A/C protein in degenerated human intervertebral disc., PMID:30536301
HiPLA: High-throughput imaging proximity ligation assay., PMID:30419336
2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society., PMID:30412778
2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: Executive summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society., PMID:30412777
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society., PMID:30412710
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society., PMID:30412709
Immunohistochemistry by anti-cleaved-Lamin A: an improved approach to tackle the misuse of glucocorticoids in cattle., PMID:30303754
Diminished Canonical β-Catenin Signaling During Osteoblast Differentiation Contributes to Osteopenia in Progeria., PMID:30001457
Elevated TGF β2 serum levels in Emery-Dreifuss Muscular Dystrophy: Implications for myocyte and tenocyte differentiation and fibrogenic processes., PMID:29693488
Secretome analysis of in vitro aged human mesenchymal stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis., PMID:29545581
Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins., PMID:29432544
Human Cytomegalovirus Nuclear Capsids Associate with the Core Nuclear Egress Complex and the Viral Protein Kinase pUL97., PMID:29342872
Biotinylation by antibody recognition-a method for proximity labeling., PMID:29256494
Nuclear organization during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes., PMID:29134302
For research use only. Not for human or drug use.
