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Anti-ALDH1A1 Antibody (R2W65)

Catalog #:   RHB85103 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC, WB
Accession: P00352
Overview

Catalog No.

RHB85103

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Aldehyde dehydrogenase, cytosolic, Retinal dehydrogenase 1, ALDH-E1, RalDH1, Aldehyde dehydrogenase family 1 member A1, ALDH1A1, ALDH1, RALDH 1, ALDC, ALHDII, PUMB1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00352

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2W65

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cerebellum tissues (left) and lung cancer (right) using ALDH1A1 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using ALDH1A1 mouse mAb against Raji (1), Jurkat (2), THP-1 (3) and K562 (4) cell lysate.
References

Multiplex single-cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer., PMID:39888143

Bevacizumab increases cisplatin efficacy by inhibiting epithelial-mesenchymal transition via ALDH1 in cervical carcinoma., PMID:39662269

Morphological and biochemical characterization of Holstein cow skin at the tail root region susceptible to Chorioptes bovis and texanus parasitism., PMID:38972752

Astragalus polysaccharides ameliorates experimental colitis by regulating memory B cells metabolism., PMID:38522565

Leveraging intracellular ALDH1A1 activity for selective cancer stem-like cell labeling and targeted treatment via in vivo click reaction., PMID:37639589

CD44-positive Cancer Stem-like Cells as a Potential Source of Peritoneal Metastasis After Surgery., PMID:37247920

Multiparametric magnetic resonance imaging for radiation therapy response monitoring in soft tissue sarcomas: a histology and MRI co-registration algorithm., PMID:37056570

Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer., PMID:36704357

Reliability of CD44, CD24, and ALDH1A1 immunohistochemical staining: Pathologist assessment compared to quantitative image analysis., PMID:36590957

ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade., PMID:35656893

Cancer stem cell markers CD44v9+/CD133- are associated with low apoptosis in both sporadic and ulcerative colitis-associated colorectal cancers., PMID:35224715

Prognostic and predictive roles of cancer stem cell markers in head and neck squamous cell carcinoma patients receiving chemoradiotherapy with or without nimotuzumab., PMID:35140342

Carboxypeptidase A4 negatively correlates with p53 expression and regulates the stemness of breast cancer cells., PMID:33746592

Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo., PMID:33482272

Molecular phenotypes of circulating tumor cells and efficacy of nivolumab treatment in patients with head and neck squamous cell carcinoma., PMID:33299117

ALDH Expression in Angiosarcoma of the Lung: A Potential Marker of Aggressiveness?, PMID:33195295

Protective Effects of ALDH1A Enzyme Inhibition on Helicobacter-Induced Colitis in Smad3-/- Mice are Associated with Altered α4ß7 Integrin Expression on Activated T Cells., PMID:32987910

The hedgehog pathway regulates cancer stem cells in serous adenocarcinoma of the ovary., PMID:32382997

CCR9 Promotes Migration and Invasion of Lung Adenocarcinoma Cancer Stem Cells., PMID:32308544

P38 Inhibition Prevents Herpes Simplex Virus Type 1 (HSV-1) Infection in Cultured Corneal Keratocytes., PMID:32250648

Functional study of acetaldehyde dehydrogenase 1 (ALDH1) in keratinocytes: microarray integrating bioinformatics approaches., PMID:32189581

Quantification of biomarkers for beef meat qualities using a combination of Parallel Reaction Monitoring- and antibody-based proteomics., PMID:32078991

Rational Design of a Red Fluorescent Sensor for ALDH1A1 Displaying Enhanced Cellular Uptake and Reactivity., PMID:31738518

[Markers of stem cells and their prognostic values for urothelial carcinomas of the urinary tract]., PMID:31162900

IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells., PMID:30518684

Whole cell melanoma vaccine genetically modified to stem cells like phenotype generates specific immune responses to ALDH1A1 and long-term survival in advanced melanoma patients., PMID:30377573

Potential function of CTLA-4 in the tumourigenic capacity of melanoma stem cells., PMID:30344757

CD163, a novel therapeutic target, regulates the proliferation and stemness of glioma cells via casein kinase 2., PMID:30258108

Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1., PMID:30159402

Expression of Aldehyde Dehydrogenase 1A1 (ALDH1A1) as a Prognostic Biomarker in Colorectal Cancer Using Immunohistochemistry., PMID:29748529

Lung cancer stem cells-origin, characteristics and therapy., PMID:29682513

Disruption of IFN-I Signaling Promotes HER2/Neu Tumor Progression and Breast Cancer Stem Cells., PMID:29622580

Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells., PMID:29604293

Tamoxifen enhances stemness and promotes metastasis of ERα36+ breast cancer by upregulating ALDH1A1 in cancer cells., PMID:29393296

Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients., PMID:29122836

Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells., PMID:28768501

EMP2 is a novel therapeutic target for endometrial cancer stem cells., PMID:28604744

Complement component C3aR constitutes a novel regulator for chick eye morphogenesis., PMID:28576690

Associations of carboxypeptidase 4 with ALDH1A1 expression and their prognostic value in esophageal squamous cell carcinoma., PMID:28475748

Aldehyde dehydrogenase 1 (ALDH1) expression is an independent prognostic factor in triple negative breast cancer (TNBC)., PMID:28383433

The 2016 Bowman Lecture Conjunctival curses: scarring conjunctivitis 30 years on., PMID:28106896

Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells., PMID:28100682

BRCA1-IRIS overexpression promotes and maintains the tumor initiating phenotype: implications for triple negative breast cancer early lesions., PMID:28052035

Label-Free Imaging of Umbilical Cord Tissue Morphology and Explant-Derived Cells., PMID:27746820

Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota., PMID:27685470

Same difference: A pilot study of cyclin D1, bcl-2, AMACR, and ALDH-1 identifies significant differences in expression between primary colon adenocarcinoma and its metastases., PMID:27623206

Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection., PMID:27193292

Prognostic Value of ALDH1, EZH2 and Ki-67 in Astrocytic Gliomas., PMID:27136105

Expression of breast cancer stem cell markers as predictors of prognosis and response to trastuzumab in HER2-positive breast cancer., PMID:27115469

The utility of STAT6 and ALDH1 expression in the differential diagnosis of solitary fibrous tumor versus prostate-specific stromal neoplasms., PMID:27068523

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-ALDH1A1 Antibody (R2W65) [RHB85103]
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