Catalog No.
RHB85103
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Aldehyde dehydrogenase, cytosolic, Retinal dehydrogenase 1, ALDH-E1, RalDH1, Aldehyde dehydrogenase family 1 member A1, ALDH1A1, ALDH1, RALDH 1, ALDC, ALHDII, PUMB1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P00352
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2W65
Multiplex single-cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer., PMID:39888143
Bevacizumab increases cisplatin efficacy by inhibiting epithelial-mesenchymal transition via ALDH1 in cervical carcinoma., PMID:39662269
Morphological and biochemical characterization of Holstein cow skin at the tail root region susceptible to Chorioptes bovis and texanus parasitism., PMID:38972752
Astragalus polysaccharides ameliorates experimental colitis by regulating memory B cells metabolism., PMID:38522565
Leveraging intracellular ALDH1A1 activity for selective cancer stem-like cell labeling and targeted treatment via in vivo click reaction., PMID:37639589
CD44-positive Cancer Stem-like Cells as a Potential Source of Peritoneal Metastasis After Surgery., PMID:37247920
Multiparametric magnetic resonance imaging for radiation therapy response monitoring in soft tissue sarcomas: a histology and MRI co-registration algorithm., PMID:37056570
Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer., PMID:36704357
Reliability of CD44, CD24, and ALDH1A1 immunohistochemical staining: Pathologist assessment compared to quantitative image analysis., PMID:36590957
ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade., PMID:35656893
Cancer stem cell markers CD44v9+/CD133- are associated with low apoptosis in both sporadic and ulcerative colitis-associated colorectal cancers., PMID:35224715
Prognostic and predictive roles of cancer stem cell markers in head and neck squamous cell carcinoma patients receiving chemoradiotherapy with or without nimotuzumab., PMID:35140342
Carboxypeptidase A4 negatively correlates with p53 expression and regulates the stemness of breast cancer cells., PMID:33746592
Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo., PMID:33482272
Molecular phenotypes of circulating tumor cells and efficacy of nivolumab treatment in patients with head and neck squamous cell carcinoma., PMID:33299117
ALDH Expression in Angiosarcoma of the Lung: A Potential Marker of Aggressiveness?, PMID:33195295
Protective Effects of ALDH1A Enzyme Inhibition on Helicobacter-Induced Colitis in Smad3-/- Mice are Associated with Altered α4ß7 Integrin Expression on Activated T Cells., PMID:32987910
The hedgehog pathway regulates cancer stem cells in serous adenocarcinoma of the ovary., PMID:32382997
CCR9 Promotes Migration and Invasion of Lung Adenocarcinoma Cancer Stem Cells., PMID:32308544
P38 Inhibition Prevents Herpes Simplex Virus Type 1 (HSV-1) Infection in Cultured Corneal Keratocytes., PMID:32250648
Functional study of acetaldehyde dehydrogenase 1 (ALDH1) in keratinocytes: microarray integrating bioinformatics approaches., PMID:32189581
Quantification of biomarkers for beef meat qualities using a combination of Parallel Reaction Monitoring- and antibody-based proteomics., PMID:32078991
Rational Design of a Red Fluorescent Sensor for ALDH1A1 Displaying Enhanced Cellular Uptake and Reactivity., PMID:31738518
[Markers of stem cells and their prognostic values for urothelial carcinomas of the urinary tract]., PMID:31162900
IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells., PMID:30518684
Whole cell melanoma vaccine genetically modified to stem cells like phenotype generates specific immune responses to ALDH1A1 and long-term survival in advanced melanoma patients., PMID:30377573
Potential function of CTLA-4 in the tumourigenic capacity of melanoma stem cells., PMID:30344757
CD163, a novel therapeutic target, regulates the proliferation and stemness of glioma cells via casein kinase 2., PMID:30258108
Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1., PMID:30159402
Expression of Aldehyde Dehydrogenase 1A1 (ALDH1A1) as a Prognostic Biomarker in Colorectal Cancer Using Immunohistochemistry., PMID:29748529
Lung cancer stem cells-origin, characteristics and therapy., PMID:29682513
Disruption of IFN-I Signaling Promotes HER2/Neu Tumor Progression and Breast Cancer Stem Cells., PMID:29622580
Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells., PMID:29604293
Tamoxifen enhances stemness and promotes metastasis of ERα36+ breast cancer by upregulating ALDH1A1 in cancer cells., PMID:29393296
Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients., PMID:29122836
Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells., PMID:28768501
EMP2 is a novel therapeutic target for endometrial cancer stem cells., PMID:28604744
Complement component C3aR constitutes a novel regulator for chick eye morphogenesis., PMID:28576690
Associations of carboxypeptidase 4 with ALDH1A1 expression and their prognostic value in esophageal squamous cell carcinoma., PMID:28475748
Aldehyde dehydrogenase 1 (ALDH1) expression is an independent prognostic factor in triple negative breast cancer (TNBC)., PMID:28383433
The 2016 Bowman Lecture Conjunctival curses: scarring conjunctivitis 30 years on., PMID:28106896
Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells., PMID:28100682
BRCA1-IRIS overexpression promotes and maintains the tumor initiating phenotype: implications for triple negative breast cancer early lesions., PMID:28052035
Label-Free Imaging of Umbilical Cord Tissue Morphology and Explant-Derived Cells., PMID:27746820
Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota., PMID:27685470
Same difference: A pilot study of cyclin D1, bcl-2, AMACR, and ALDH-1 identifies significant differences in expression between primary colon adenocarcinoma and its metastases., PMID:27623206
Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection., PMID:27193292
Prognostic Value of ALDH1, EZH2 and Ki-67 in Astrocytic Gliomas., PMID:27136105
Expression of breast cancer stem cell markers as predictors of prognosis and response to trastuzumab in HER2-positive breast cancer., PMID:27115469
The utility of STAT6 and ALDH1 expression in the differential diagnosis of solitary fibrous tumor versus prostate-specific stromal neoplasms., PMID:27068523