Catalog No.
RHB53202
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
Homeobox protein Nkx-2.2, NKX2-2, Homeobox protein NK-2 homolog B, NKX2B, NKX2.2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95096
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2W15
The Extensive Case Series of 21 CIC::DUX4, 18 BCOR::CCNB3 and 148 Ewing's Sarcomas From a Single Center., PMID:40298239
NKX2-2 based nuclei sorting on frozen human archival pancreas enables the enrichment of islet endocrine populations for single-nucleus RNA sequencing., PMID:38689254
Expression of NKX2.2 in Non-Ewing Tumors With Round Cell Morphology., PMID:38234938
Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis., PMID:36405721
[Expression and diagnostic value of NKX3.1 and NKX2.2 in mesenchymal chondrosarcoma]., PMID:35152629
Targeting CD99 Compromises the Oncogenic Effects of the Chimera EWS-FLI1 by Inducing Reexpression of Zyxin and Inhibition of GLI1 Activity., PMID:34667115
Differential Morphological Diagnosis of Various Forms of Congenital Hyperinsulinism in Children., PMID:34497584
Bone marrow trephine immunohistochemistry is useful in characterizing malignancy-associated myelonecrosis: A retrospective observational study., PMID:34342935
Diagnostic Immunohistochemistry of Soft Tissue and Bone Tumors: An Update on Biomarkers That Correlate with Molecular Alterations., PMID:33921435
Extraskeletal Ewing's Sarcoma with CD7 Positivity and T-cell Receptor/Immunoglobulin Rearrangement Masquerading as T-lymphoblastic Lymphoma., PMID:33213248
NKX3.1 immunoreactivity is not identified in mesenchymal chondrosarcoma: a 25-case cohort study., PMID:32779239
Sirt2 epigenetically down-regulates PDGFRα expression and promotes CG4 cell differentiation., PMID:31020898
PAX7 immunohistochemical evaluation of Ewing sarcoma and other small round cell tumours., PMID:29920735
NKX2.2, PDX-1 and CDX-2 as potential biomarkers to differentiate well-differentiated neuroendocrine tumors., PMID:29713473
Immunohistochemical analysis of NKX2.2, ETV4, and BCOR in a large series of genetically confirmed Ewing sarcoma family of tumors., PMID:28864350
The Utility of NKX2.2 and TLE1 Immunohistochemistry in the Differentiation of Ewing Sarcoma and Synovial Sarcoma., PMID:28800015
Generation and isolation of oligodendrocyte progenitor cells from human pluripotent stem cells., PMID:26134954
In Vitro Differentiation of Pluripotent Stem Cells into Functional β Islets Under 2D and 3D Culture Conditions and In Vivo Preclinical Validation of 3D Islets., PMID:25783769
Mammalian Nkx2.2+ perineurial glia are essential for motor nerve development., PMID:24979729
Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet., PMID:23884882
Generation of mice encoding a conditional allele of Nkx2.2., PMID:23494546
Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes., PMID:23269676
NKX2.2 is a useful immunohistochemical marker for Ewing sarcoma., PMID:22446943
Induction and selection of Sox17-expressing endoderm cells generated from murine embryonic stem cells., PMID:22123608
Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation., PMID:20538404
Electrical stimulation of the medullary pyramid promotes proliferation and differentiation of oligodendrocyte progenitor cells in the corticospinal tract of the adult rat., PMID:20493923
MafA promotes the reprogramming of placenta-derived multipotent stem cells into pancreatic islets-like and insulin+ cells., PMID:20158571
CD52 expression is induced in the mouse uterus at the time of embryo implantation., PMID:19735946
Statin therapy inhibits remyelination in the central nervous system., PMID:19349355
Rapid induction of genes associated with tissue protection and neural development in contused adult spinal cord after radial glial cell transplantation., PMID:19257808
Mesenchymal stem cells derived from human exocrine pancreas express transcription factors implicated in beta-cell development., PMID:18580448
Signals from the neural crest regulate beta-cell mass in the pancreas., PMID:18506029
Pax6 regulates the identity of embryonic diencephalic neurons., PMID:11161479
For research use only. Not for human or drug use.
