Catalog No.
RHA57302
Species reactivity
Human, Rat
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, WB: 1:500-1:2000
Target
Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein, KDM6A, Lysine-specific demethylase 6A, Ubiquitously-transcribed TPR protein on the X chromosome, Histone demethylase UTX, UTX, [histone H3]-trimethyl-L-lysine(27) demethylase 6A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O15550
Applications
ELISA, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2U77
Brief research report: WGCNA-driven identification of histone modification genes as potential biomarkers in AQP4-Associated optic neuritis., PMID:39238786
Conserved role of hnRNPL in alternative splicing of epigenetic modifiers enables B cell activation., PMID:38744970
XX sex chromosome complement modulates immune responses to heat-killed Streptococcus pneumoniae immunization in a microbiome-dependent manner., PMID:38486287
Autoimmune cytopenia and Kabuki syndrome in paediatrics: Insights in 11 patients., PMID:38432067
Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma., PMID:38355622
XX sex chromosome complement modulates immune responses to heat-killed Streptococcus pneumoniae immunization in a microbiome-dependent manner., PMID:37961596
Somatic alterations of TP53 and MDM2 associated with response to enfortumab vedotin in patients with advanced urothelial cancer., PMID:37091148
KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer., PMID:36306422
Case report: A study on the de novo KMT2D variant of Kabuki syndrome with Goodpasture's syndrome by whole exome sequencing., PMID:36090579
Advances in the Treatment of Hairy Cell Leukemia Variant., PMID:35178674
AZFa candidate gene UTY and its X homologue UTX are expressed in human germ cells., PMID:35128450
Clinical heterogeneity of Kabuki syndrome in a cohort of Italian patients and review of the literature., PMID:34232366
X chromosome escapee genes are involved in ischemic sexual dimorphism through epigenetic modification of inflammatory signals., PMID:33712031
Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma., PMID:33008426
A Rare Cause of Hyperinsulinemic Hypoglycemia: Kabuki Syndrome., PMID:32830475
Dramatic increase in gene mutational burden after transformation of follicular lymphoma into TdT+ B-lymphoblastic leukemia/lymphoma., PMID:31776129
Demethylase Kdm6a epigenetically promotes IL-6 and IFN-β production in macrophages., PMID:28284523
Mild humoral immunodeficiency in a patient with X-linked Kabuki syndrome., PMID:26701671
T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX., PMID:26431949
Epigenetic control of the immune system: a lesson from Kabuki syndrome., PMID:26411453
For research use only. Not for human or drug use.
