Catalog No.
YHD15001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Tyr143
Predicted molecular weight
17.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P16104
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
H2a/x, Histone H2A.X, H2AFX, Histone H2AX, H2AX
AS-IV Attenuates Oxidative Stress-Induced Apoptosis in Zebrafish via Modulation of the AKT/NRF2/HO-1/Caspase-3 Signaling Axis., PMID:40509241
Vat-Mediated Mucus Penetration Enables Genotoxic Activity of pks+ Escherichia coli., PMID:40508162
Polystyrene microplastics induces the injury of human corneal epithelial cells through ROS-mediated p53 pathway., PMID:40503930
Genotoxic interaction between deoxynivalenol and acrylamide., PMID:40467221
circ_0002456/FUS interaction inhibits NF-κB signaling to attenuate DNA damage and inflammatory responses in hDPSCs., PMID:40457486
Hinokitiol Protects RPE cells from Oxidative and Autophagic Dysfunction: Implications for AMD Therapy., PMID:40447166
Effect of X-Ray Energy on the Quantitative Yield of γH2AX and 53BP1 Foci in Human Mesenchymal Stem Cells., PMID:40442472
Robotic radiation shielding system reduces radiation-induced DNA damage in operators performing electrophysiological procedures., PMID:40437055
The Stem Cell Transcription Factor OCT4 Silences Target DNA Methyltransferase 1 to Strengthen DNA Damage Response in Cisplatin-Treated Gastric Cancer Cells., PMID:40433841
C1QBP Modulates DNA Damage Response and Radiosensitivity in Hepatocellular Carcinoma by Regulating NF-κB Activity., PMID:40429658
Synergistic activity of S63845 and parthenolide to overcome acquired resistance to MEK1/2 inhibitor in melanoma cells: Mechanisms and therapeutic potential., PMID:40424823
Neuroprotective effect of folic acid by maintaining DNA stability and mitochondrial homeostasis through the ATM/CHK2/P53/PGC-1α pathway in alcohol-exposed mice., PMID:40421718
Chemical-Induced DNA Damage Identification by High-Throughput Detection of DNA Double-Strand Break., PMID:40418481
Radiation-Induced Gamma-H2AX Foci Staining and Analysis., PMID:40418470
Locoregional radionuclide therapy of glioblastoma with [211At]At-PDA-FAPI., PMID:40415095
Far-ultraviolet light causes direct DNA damage in human lung cells and tissues., PMID:40410349
Short-Term and Long-Term Effects of Electronic Cigarettes on Mouse Lungs Following Nose-Only Exposures., PMID:40401807
Increased DNA damage/repair response in placentas from women infected with COVID-19 in pregnancy., PMID:40393216
αB-crystallin enhances radioresistance in basal-like breast cancer cells by suppressing caspase-3 activation., PMID:40390653
PRDX1 protects ATM from arsenite-induced proteotoxicity and maintains its stability during DNA damage signaling., PMID:40387816
Low expression of miR-7-5p promotes resistance to radiotherapy in lung cancer through direct upregulation of PKP2 expression., PMID:40374728
Chronic arsenic exposure of ovarian surface and fallopian tube cultures induces giant and/or multinucleated cells with phagocytosis-like properties and an inflammatory phenotype., PMID:40368219
The role of tungsten in modulating DNA double-strand break repair and class switch recombination., PMID:40360058
Discovery of novel β-carboline/melatonin hybrids as STAT3 inhibitors for the treatment of lung cancer via increasing DNA damage., PMID:40354674
Artesunate Enhances Sensitivity of Renal Cancer Cells to Sunitnib by Mediating Tripartite Motif Containing 24-Induced Ubiquitination of Paired Box 6., PMID:40346910
HBV-induced N6 methyladenosine modification of PARP1 enhanced AFB1-related DNA damage and synergistically contribute to HCC., PMID:40344782
HIV-Tat upregulates the expression of senescence biomarkers in CD4+ T-cells., PMID:40342418
High-LET Proton Irradiation Significantly Alters the Clonogenic and Tumorigenic Potential of Human Breast Cancer Cell Lines In Vitro and In Vivo., PMID:40302350
Mechanisms of Ellagic Acid (EA)-Mediated Osteogenic Differentiation of Human Dental Pulp-Derived Stem Cells., PMID:40290905
Impact of sodium-glucose cotransporter-2 inhibitors on aging biomarkers and plasma ceramide levels in type 2 diabetes: beyond glycemic control., PMID:40289660
3D printed microtissue cassettes enabling high throughput proton radiobiological assays., PMID:40288869
Tylophora yunnanensis extract inhibits cholesterol biosynthesis to suppress triple negative breast cancer., PMID:40287115
Cigarette sidestream smoke-induced cellular senescence and the protective role of histone H2AX., PMID:40286947
Evaluating dermal toxicity of the flame retardant aluminum diethylphosphinate by in silico-in vitro testing strategy., PMID:40286754
Integrated lncRNA and mRNA Transcriptome Analyses of IGF1 and IGF2 Stimulated Ovaries Reveal Genes and Pathways Potentially Associated with Ovarian Development and Oocyte Maturation in Golden Pompano (Trachinotus ovatus)., PMID:40281968
SOX5 inhibition overcomes PARP inhibitor resistance in BRCA-mutated breast and ovarian cancer., PMID:40274769
Subcellular functions of tau mediate repair response and synaptic homeostasis in injury., PMID:40269186
p14ARF interacts with γ-H2AX and is involved in the DNA damage response., PMID:40267841
Detection of γ-H2A.X for Rapid Assessment of Genotoxic Agent-induced Double-strand DNA Breaks by Immunofluorescence., PMID:40257558
Trabectedin Induces Synthetic Lethality via the p53-Dependent Apoptotic Pathway in Ovarian Cancer Cells Without BRCA Mutations When Used in Combination with Niraparib., PMID:40243501
Blocking triggering receptors expressed on myeloid cell-1 alleviates alveolar epithelial cell senescence by inhibiting oxidative stress in pulmonary fibrosis., PMID:40240638
FOXA1 Targets NEK2 to Mediate Cisplatin Resistance in Lung Adenocarcinoma Cells by Activating DNA Damage Repair., PMID:40233258
CHK1 inhibition overcomes gemcitabine resistance in non-small cell lung cancer cell A549., PMID:40226818
Vascular smooth muscle cell-derived SO2 sulphenylated interferon regulatory factor 1 to inhibit VSMC senescence., PMID:40223932
Metabolomic Reprogramming Induced by Benzo[a]pyene in Skin Keratinocytes and Protective Effects of Glutathione Amino Acid Precursors., PMID:40208244
Rosa roxburghii juice alleviates DEHP-induced reproductive system damage in male mice via the PI3K/AKT signaling pathway., PMID:40185256
Overexpression of METTL3 in lung cancer cells inhibits radiation-induced bystander effect., PMID:40184791
Identification of RASL11A as a gene conferring radiosensitivity in glioblastoma., PMID:40167966
SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity., PMID:40164578
Annexin A2 binds the 3'-UTR of H2AX mRNA and regulates histone-H2AX-derived hypoxia-inducible factor 1-alpha activation., PMID:40164417
For research use only. Not for human or drug use.
