Catalog No.
MXX25501
Species reactivity
Neisseria meningitidis (strain alpha14)
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Immunogen
Recombinant Neisseria meningitidis pilin protein.
Tested applications
ELISA: 1:1000-1:10000, WB: 1:500-1:2000
Endotoxin level
Please contact with the lab for this information.
Purification
Protein A/G purified from cell culture supernatant.
Accession
C6S5G8
Applications
ELISA, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Alternative Names
Putative type IV pilin protein, NMO_0429, pilin protein
Clone ID
m1A03
Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms., PMID:38499587
Pilus PilA of the naturally competent HACEK group pathogen Aggregatibacter actinomycetemcomitans stimulates human leukocytes and interacts with both DNA and proinflammatory cytokines., PMID:36374775
The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus., PMID:34725157
Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation., PMID:26367394
Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci., PMID:23028802
The meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signaling to endothelial cells., PMID:22778100
Recombinant outer membrane secretin PilQ(406-770) as a vaccine candidate for serogroup B Neisseria meningitidis., PMID:22234267
Testing the vaccine potential of PilV, PilX and ComP, minor subunits of Neisseria meningitidis type IV pili., PMID:21803096
Transplacental transport of IgG antibodies specific for pertussis, diphtheria, tetanus, haemophilus influenzae type b, and Neisseria meningitidis serogroup C is lower in preterm compared with term infants., PMID:20803841
Sequence conservation of pilus subunits in Neisseria meningitidis., PMID:20457291
Neisseria meningitidis differentially controls host cell motility through PilC1 and PilC2 components of type IV Pili., PMID:19718432
Development of immunity to serogroup B meningococci during carriage of Neisseria meningitidis in a cohort of university students., PMID:15501781
Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili., PMID:15249686
Type IV pilus retraction in pathogenic Neisseria is regulated by the PilC proteins., PMID:15103324
Analysis of the role of pglI in pilin glycosylation of Neisseria meningitidis., PMID:15094166
Identification and characterization of pptA: a gene involved in the phase-variable expression of phosphorylcholine on pili of Neisseria meningitidis., PMID:14638777
Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo., PMID:12183570
Bordetella pertussis fimbriae are effective carrier proteins in Neisseria meningitidis serogroup C conjugate vaccines., PMID:11549423
Identification of a novel gene involved in pilin glycosylation in Neisseria meningitidis., PMID:9767566
Pilus-mediated adhesion of Neisseria meningitidis: the essential role of cell contact-dependent transcriptional upregulation of the PilC1 protein., PMID:9680205
The pathogenic neisseriae contain an inactive rpoN gene and do not utilize the pilE sigma54 promoter., PMID:9479056
Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria., PMID:9379894
Characterization of a class II pilin expression locus from Neisseria meningitidis: evidence for increased diversity among pilin genes in pathogenic Neisseria species., PMID:9199428
Anti-Gal binds to pili of Neisseria meningitidis: the immunoglobulin A isotype blocks complement-mediated killing., PMID:7591153
Functional implications of the expression of PilC proteins in meningococci., PMID:8577245
Antigenic and epidemiologic properties of the ET-37 complex of Neisseria meningitidis., PMID:8501321
Antigenic variation of pilin regulates adhesion of Neisseria meningitidis to human epithelial cells., PMID:8332064
Clonal and antigenic analysis of serogroup A Neisseria meningitidis with particular reference to epidemiological features of epidemic meningitis in the People's Republic of China., PMID:1452360
Expression of the Opc protein correlates with invasion of epithelial and endothelial cells by Neisseria meningitidis., PMID:1435257
A comparison of the variable antigens expressed by clone IV-1 and subgroup III of Neisseria meningitidis serogroup A., PMID:1370175
Identification of epitopes recognized by monoclonal antibodies SM1 and SM2 which react with all pili of Neisseria gonorrhoeae but which differentiate between two structural classes of pili expressed by Neisseria meningitidis and the distribution of their encoding sequences in the genomes of Neisseria spp., PMID:2483993
Colony morphology of piliated Neisseria meningitidis., PMID:2572672
Cloning and characterization of the structural gene for the class 2 protein of Neisseria meningitidis., PMID:2545623
New concepts in vaccines for mucosal non-enteric human bacterial pathogens., PMID:2481958
Common epitopes of pilin of Neisseria meningitidis., PMID:2457056
Neisseria meningitidis C114 contains silent, truncated pilin genes that are homologous to Neisseria gonorrhoeae pil sequences., PMID:2895102
Inter-strain homology of pilin gene sequences in Neisseria meningitidis isolates that express markedly different antigenic pilus types., PMID:2889791
Evidence of serum antibodies to Neisseria gonorrhoeae before gonococcal infection., PMID:2883240
Variation in the expression of pili and outer membrane protein by Neisseria meningitidis during the course of meningococcal infection., PMID:2878967
An unusual Neisseria isolated from conjunctival cultures in rural Egypt., PMID:2873189
Pili of Neisseria meningitidis. Analysis of structure and investigation of structural and antigenic relationships to gonococcal pili., PMID:2409203
Structural and antigenic analysis of meningococcal piliation., PMID:2580788
Immunogenicity of meningococcal antigens as detected in patient sera., PMID:6131872
Cell-mediated immune response in gonococcal infection., PMID:6111387
Gonococcal ribosomes as skin test antigens. II. Precision Of the Method, Attempts To Identify The Ribosomal Antigen, and Correlation with The Macrophage Migration Inhibition test., PMID:816414
For research use only. Not for human or drug use.
