Catalog No.
                        MHC15803
                        
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Species reactivity
                        
                        Human, Mouse, Rat, Rabbit                        
                                                
                                            Host species
                        
                        Mouse                        
                                                
                                            Isotype
                        
                        IgG2b                        
                                                
                                            Clonality
                        
                        Monoclonal                        
                                                
                                            Immunogen
                        
                        Recombinant Human IL6 Protein.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            
                                            Purification
                        
                        Protein A/G purified from cell culture supernatant.                        
                                                
                                            Accession
                        
                        P05231                        
                                                
                                            
                                            Applications
                        
                        FCM, IHC                        
                                                
                                            Form
                        
                        Liquid                        
                                                
                                            Storage buffer
                        
                        0.01M PBS, 0.05% Sodium Azide.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months. 
Store at -80°C long term.                        
                                                
                                            
                                            
                                                Alternative Names
                            Hybridoma growth factor, BSF-2, IFN-beta-2, CDF, IL6, Interleukin-6, IL-6, B-cell stimulatory factor 2, Interferon beta-2, IFNB2, CTL differentiation factor
                            
                                                        Clone ID
                            1A496
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            Pro-dermcidin and derivatives as potential therapeutics for lethal experimental sepsis., PMID:40534887
                                            Direct Interleukin-6 Inhibition Blunts Arterial Thrombosis by Reducing Collagen-Mediated Platelet Activation., PMID:40534557
                                            Optimised nanobody-based quenchbodies for enhanced protein detection., PMID:40533519
                                            Conserved domains of flagellin as adjuvants for an inactivated vaccine against porcine epidemic diarrhea virus., PMID:40532846
                                            Immune response to and virological profile of SARS-CoV-2 before and after symptom onset in individuals vaccinated with inactivated COVID-19 vaccines., PMID:40530661
                                            Inflammatory signatures and immunomodulation in neonates: a pilot study., PMID:40525368
                                            Generation and Biological Characterization of an Anti-IL-6Rα Biosimilar Candidate Antibody., PMID:40524396
                                            Pilot study of ABO-isogroup or universal plasma pools with or without pathogen reduction treatment., PMID:40522315
                                            TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation., PMID:40512402
                                            Role of Ocrelizumab in modulating gene and microRNA expression in multiple sclerosis., PMID:40510879
                                            A Mixture of Free and Microencapsulated Essential Oils Combined with Turmeric and Tannin in the Diet of Dairy Cows: Effects on Productive Efficiency and Animal Health., PMID:40509055
                                            Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies., PMID:40507880
                                            FcRn inhibitors in immune thrombocytopenia: A comprehensive review of therapeutic advances and clinical outcomes., PMID:40505332
                                            CTRP7 as a molecular biomarker associating with responsiveness to pulmonary vasodilators: insights from human and animal studies in pulmonary arterial hypertension., PMID:40504501
                                            Inflammatory arthritis immune related adverse events represent a unique autoimmune disease entity primarily driven by T cells, but likely not autoantibodies., PMID:40502578
                                            Chronic administration of morphine provokes generation of antibodies to morphine and immunosuppression in individuals with opioid use disorder., PMID:40501089
                                            Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215
                                            Effects of Rhodobacter sphaeroides protein on growth performance, nutrient digestibility, rumen fermentation, and serum metabolites in dairy calves during the pre- and postweaning periods., PMID:40499903
                                            Activin A exacerbates neonatal necrotizing enterocolitis via ALK4-mediated apoptosis and barrier disruption., PMID:40494204
                                            The role of cytokines in pediatric hematologic malignancies: mechanisms of tumor progression and therapeutic implications - a narrative review., PMID:40486628
                                            Adaptive immune changes in colorectal cancer: a focus on T and B cell activation genes., PMID:40484866
                                            [Correlation between soluble CD146 and systemic vasculitis]., PMID:40484821
                                            Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice., PMID:40464222
                                            Glutamine and Isoleucine as the Key Amino Acids in Major IgE Linear Epitopes of α-Lactalbumin Identified by the Immune Peptide Microarray Assay For Chinese Bovine Milk Allergy., PMID:40462490
                                            RNase 7 and Th cytokines synergistically increase the secretion of interleukin-6 from keratinocytes., PMID:40461723
                                            IL-6: a pivotal molecule for tumor-brain dysfunction interaction., PMID:40461299
                                            Alternation of anti-NMDA receptor subunit GluN2 antibody in a patient with SLE who promptly developed anxiety after belimumab., PMID:40455606
                                            Toll-like receptor engaged in activation and osteoimmuno-cytokines production by unswitched memory B cells during periodontitis., PMID:40455294
                                            Several Common Genetic Variations Associate With Functional or Anatomic Effects of Anti-VEGF Treatment in Conditions With Macular Edema., PMID:40455044
                                            The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis., PMID:40454313
                                            Longitudinal analysis of cytokine dynamics in severe fever with thrombocytopenia syndrome patients - High-incidence regions of China (2010-2023)., PMID:40453472
                                            A Spanish Porcine Reproductive and Respiratory Syndrome Virus 1 Strain Is Highly Virulent in Pigs Under Experimental Conditions., PMID:40453458
                                            Multi-omics analysis reveals Angelica sinensis-Carthamus tinctorius herb pair ameliorates diabetic retinopathy comorbid with depressive symptoms via the gut-eye-brain axis., PMID:40449450
                                            Immune responses and recovery from spotty liver disease in layer birds., PMID:40446677
                                            The recombinant anti-MET/EpCAM bispecific antibody fragment: a promising novel therapeutic approach for breast cancer treatment., PMID:40445574
                                            Soil-Transmitted Helminths and the Intricacies of Immunoregulation: Evidence From Amazonian Ecuador for the Importance of Considering Species-Specific Effects Within the Old Friends Hypothesis., PMID:40444920
                                            Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control Study., PMID:40441712
                                            Epstein-Barr virus infection increases the risk of depression: A cross-sectional study and Mendelian randomization analysis., PMID:40441653
                                            Immunostimulatory effects of multiple short-hairpin RNAs enhance foot-and-mouth disease vaccine-induced humoral immunity., PMID:40441607
                                            Antibody-mediated Rejection - Treatment Standard., PMID:40440205
                                            Itaconate derivative 4-OI inhibits M1 macrophage polarization and restores its impaired function in immune thrombocytopenia through metabolic reprogramming., PMID:40437667
                                            IL-6 Inhibitors and TNF Inhibitors: Impact on Exercise-induced Cardiac Adaptations in Patients With Rheumatoid Arthritis., PMID:40436519
                                            A case of Schnitzler syndrome complicated by rheumatoid arthritis treated with methotrexate., PMID:40433863
                                            A Modular Mathematical Model of the Immune Response for Investigating the Pathogenesis of Infectious Diseases., PMID:40431602
                                            OVA-Induced Food Allergy Leads to Neurobehavioral Changes in Mice and the Potential Role of Gut Microbiota and Metabolites Dysbiosis., PMID:40429903
                                            C1q Binds to CD4+ T Cells and Inhibits the Release of Pro-Inflammatory Cytokines: Role in the Pathogenesis of Systemic Lupus Erythematosus., PMID:40429614
                                            Immunocytokines and cytokine neutralization for cancer immunotherapy., PMID:40425444
                                            Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia., PMID:40424990
                                            Phase 1b/2 study of ADG106, a 4-1BB/CD137 agonist, in combination with toripalimab in patients with advanced solid tumors., PMID:40421181
                                            [Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135