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Anti-MADD Antibody (R2R77)

Catalog #:   RHN79201 Specific References (9) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: Q8WXG6
Overview

Catalog No.

RHN79201

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000

Target

IG20, MADD, KIAA0358, DENN, Differentially expressed in normal and neoplastic cells, Rab3 GDP/GTP exchange factor, Insulinoma glucagonoma clone 20, MAP kinase-activating death domain protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8WXG6

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2R77

Data Image
  • Immunofluorescence
    Immunocytochemistry analysis of DENN (green) in hela using DENN antibody,and DAPI(blue)
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human breast cancer using DENN antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of DENN in Hela, A549, HL-60 lysates using DENN antibody.
References

Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR Encephalitis., PMID:34584012

Specific heparan sulfate modifications stabilize the synaptic organizer MADD-4/Punctin at Caenorhabditis elegans neuromuscular junctions., PMID:33983408

Inhibition of the mTORC pathway in the antiphospholipid syndrome., PMID:25054716

MADD/DENN/Rab3GEP functions as a guanine nucleotide exchange factor for Rab27 during granule exocytosis of rat parotid acinar cells., PMID:23702376

Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons., PMID:16794604

Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement., PMID:15232311

Implication of TNF receptor-I-mediated extracellular signal-regulated kinases 1 and 2 (ERK1/2) activation in growth of AIDS-associated Kaposi's sarcoma cells: a possible role of a novel death domain protein MADD in TNF-alpha-induced ERK1/2 activation in Kaposi's sarcoma cells., PMID:10092829

The human DENN gene: genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22., PMID:9796103

DENN, a novel human gene differentially expressed in normal and neoplastic cells., PMID:8988362

Datasheet

Document Download

Anti-MADD Antibody (R2R77).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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For research use only. Not for human or drug use.

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Anti-MADD Antibody (R2R77) [RHN79201]
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