Catalog No.
YHD06501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala753-Pro973
Predicted molecular weight
28.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14735
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Insulysin, IDE, Abeta-degrading protease, Insulin protease, Insulinase, Insulin-degrading enzyme
Insulin-Degrading Enzyme Regulates mRNA Processing and May Interact with the CCR4-NOT Complex., PMID:40497968
C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation., PMID:40490364
Unraveling novel mechanisms of ATP-Binding cassette (ABC) transporter in insulin Resistance-induced amyloidogenesis., PMID:40482009
Scoping Review on Strategies for Safe Nucleot(s)ide Analogue Discontinuation and Optimising Functional Cure in Chronic Hepatitis B., PMID:40478218
Markers of Hepatic Insulin Clearance and Their Association With Steatosis in Hyperinsulinaemic Horses., PMID:40476757
Iron status at early pregnancy is associated with infectious respiratory and gastric illness in women receiving routine iron supplementation: the NuPED prospective cohort., PMID:40468238
Targeting FLT3 Mutations in Acute Myeloid Leukemia: The Role of Quizartinib in Precision Medicine., PMID:40456703
Decreased expression of insulin-degrading enzyme increases gluconeogenesis and glucose production in cultured hepatocytes administered with glucagon., PMID:40450129
DeepUSPS: Deep Learning-Empowered Unconstrained-Structural Protein Sequence Design., PMID:40448386
Effects of Combination Treatment with Leptin and Liraglutide on Glucose Metabolism in Insulin-Dependent Diabetic Mice., PMID:40429740
HIF1A Regulates Rhbg Expression to Enhance Ammonia Excretion in Amur Ide (Leuciscus waleckii) Under Extreme Alkaline Conditions., PMID:40427687
Mutagenesis Targeting the S153 Residue Within the Transmembrane β-Hairpin of Mosquito-Larvicidal Mpp46Ab Affects Its Toxicity and the Synergistic Toxicity with Cry4Aa., PMID:40427678
Overrange dilution for improvement of hepatitis B core related antigen as a biomarker: protocol validation and examples for application., PMID:40393306
Direct insertion of an ion channel immobilized on a soft agarose gel bead into a lipid bilayer: an optimized method., PMID:40392479
Recurrence risk factors for chronic hepatitis B virus-infected patients who achieve functional cure with pegylated interferon-α-2b-based therapy: a multicenter pilot study., PMID:40390028
Dynamics of HBV biomarkers during nucleos(t)ide analog treatment: A 14-year study., PMID:40377494
A novel chemiresistive biosensor utilizing green-synthesized AgNPs and MWCNT-ZnO nanofibers for rapid detection of tuberculosis Lipoarabinomannan (LAM) antigen., PMID:40374244
Salicylamide derivatives as potent HBV inhibitors: insights into structure-activity relationships., PMID:40352669
Hematologic and lymphatic disorders associated with chimeric antigen receptor T-cell therapy: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database., PMID:40346502
Nanomaterial Enhances the Performance of Amyloid-beta Biosensing for Alzheimer's Disease Diagnosis., PMID:40337966
Functional Cure for Hepatitis B Virus: Challenges and Achievements., PMID:40332208
The Intrinsically Disordered Region of HBx and Virus-Host Interactions: Uncovering New Therapeutic Approaches for HBV and Cancer., PMID:40332052
The Role of Neprilysin and Insulin-Degrading Enzyme in the Etiology of Sporadic Alzheimer's Disease., PMID:40300834
Immune Checkpoint Inhibitor-induced Uveitis: Disproportionality and Timing Analyses of the Japanese Pharmacovigilance Database., PMID:40295055
Synergistic effect of lactopeptide and ectoine on delaying yellowing and maintaining the postharvest quality of pak choi (Brassica rapa subsp. chinensis)., PMID:40294671
Chronic Hepatitis B in the Transplant Setting: A 30-Year Experience in a Single Tertiary Italian Center., PMID:40284897
Computed Tomography-Measured Cranial Sternal Lymphadenomegaly Is Associated with Elevated C-Reactive Protein in Small Dogs with Non-Neoplastic Disorders., PMID:40284858
Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications., PMID:40279260
Sirtuin 2 inhibitor AGK2 exerts antiviral effects by inducing epigenetic suppression of hepatitis B virus covalently closed circular DNA through recruitment of repressive histone lysine methyltransferases and reduction of cccDNA., PMID:40270769
Discussion on the duration of response following HBsAg clearance in patients with chronic hepatitis B treated with PegIFNα-2b., PMID:40264777
Entecavir for children and adults with chronic hepatitis B., PMID:40260837
Limitations and challenges in the characterization of extracellular vesicles from stem cells and serum., PMID:40259021
The Effect of MAFLD on Hepatocarcinogenesis in HBeAg-negative Patients with Undetectable HBV-DNA under NA Therapy: A Multicenter Study., PMID:40240151
The HBV variant CpF97L supports the secretion of pgRNA-containing virions at a level much greater than WT HBV., PMID:40231820
Peanut challenges prior to oral immunotherapy demonstrate high tolerance rates in selected patients., PMID:40201038
Evidence for effective suppression of INa and IK(DR) by AS2034178 (bis{2-[(4-{(4'-(2-hydroxyethoxy)-2'-methyl[1,1'-biphenyl]-3-yl)methoxy}phenyl]methyl]-3,5-dioxo-1,2,4-oxadiazolidin-4-ide} tetrahydrate), an agonist of free fatty acid receptor., PMID:40180209
Ginsenoside CK modulates glucose metabolism via PPARγ to ameliorate SCOP-induced cognitive dysfunction., PMID:40178645
Successful sequential application of CAR T-cell-therapies in relapsed refractory multiple myeloma., PMID:40178605
Selective effects of collagen-derived peptides Pro-Hyp and Hyp-Gly on the proliferation and differentiation of SSEA3-positive human dental pulp stem cells., PMID:40170801
Genomic regions occupied by both RARα and VDR are involved in the convergence and cooperation of retinoid and vitamin D signaling pathways., PMID:40167329
Impacts of high mobility group box protein 1 gene polymorphisms on morbidity and mortality after living donor liver transplantation., PMID:40157616
Replication-dependent histone labeling dissects the physical properties of euchromatin/heterochromatin in living human cells., PMID:40153514
Induction of hepatitis B core protein aggregation targeting an unconventional binding site., PMID:40135596
NEDD4-binding protein 1 suppresses hepatitis B virus replication by regulating viral RNAs., PMID:40111401
Nucleos(t)ide analogs continuation is not associated with a lower risk of HBsAg seroreversion following PEG-IFN-induced HBsAg loss., PMID:40108632
Potency of agarose gel-supported lipid bilayers for electrophysiologic analysis of channel pores formed by Bacillus thuringiensis insecticidal proteins., PMID:40098311
Making Every Penny Count: Kinase Signaling Transduction, Copper Homeostasis, & Nutrient Sensing., PMID:40089146
Characterization of the Long-distance Dispersal Kernel of White-Tailed Deer and Evaluating its Impact on Chronic Wasting Disease Spread in Wisconsin., PMID:40080236
Postoperative Analgesia and Length of Hospital Stay After Surgery for Malignant Pleural Mesothelioma: A Retrospective Observational Study., PMID:40078644
Low-Level Viremia Impairs Efficacy of Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma., PMID:40078069
For research use only. Not for human or drug use.
