Catalog No.
RHN73601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Synovial apoptosis inhibitor 1, E3 ubiquitin-protein ligase synoviolin, KIAA1810, HRD1, SYVN1, RING-type E3 ubiquitin transferase synoviolin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q86TM6
Applications
FCM, IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2Q98
Calnexin promotes the folding of mutant iduronate 2-sulfatase related to mucopolysaccharidosis type II., PMID:31029429
Human Cytomegalovirus Tropism Modulator UL148 Interacts with SEL1L, a Cellular Factor That Governs Endoplasmic Reticulum-Associated Degradation of the Viral Envelope Glycoprotein gO., PMID:29997207
The endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B cell development in mice., PMID:29907570
Inhibitory effects of ubiquitination of synoviolin by PADI4., PMID:29039504
The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development., PMID:27568564
The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation., PMID:23363602
Synovial synoviolin in relation to response to TNF blockade in patients with rheumatoid arthritis and psoriatic arthritis., PMID:22345123
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels., PMID:21987572
Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression., PMID:20976214
SEL1L and HRD1 are involved in the degradation of unassembled secretory Ig-mu chains., PMID:18314878
Overexpression of synoviolin in peripheral blood and synoviocytes from rheumatoid arthritis patients and continued elevation in nonresponders to infliximab treatment., PMID:16802346
Identification of a crucial site for synoviolin expression., PMID:16055742
For research use only. Not for human or drug use.
