Catalog No.
RHN73103
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200
Target
TBLYM, TBX21, Transcription factor TBLYM, T-box protein 21, T-box transcription factor TBX21, TBET, T-cell-specific T-box transcription factor T-bet
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UL17
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2Q90
Influence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia., PMID:40313965
T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis., PMID:40107244
NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model., PMID:39932765
Isoprinosine as a foot-and-mouth disease vaccine adjuvant elicits robust host defense against viral infection through immunomodulation., PMID:38510965
Frontline Management of Nodal Peripheral T-Cell Lymphomas., PMID:37262395
Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis., PMID:36966145
Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells., PMID:36813963
In vitro treatment of murine splenocytes with extracellular vesicles derived from mesenchymal stem cells altered the mRNA levels of the master regulator genes of T helper cell subsets., PMID:36720794
IFN-γ promotes the development of systemic lupus erythematosus through the IFNGR1/2-PSTAT1-TBX21 signaling axis., PMID:36398225
Genetic Diagnosis of Inborn Errors of Immunity in an Emerging Country: a Retrospective Study of 216 Moroccan Patients., PMID:36367635
Myelin oligodendrocyte glycoprotein-associated disease is associated with BANK1, RNASET2 and TNIP1 polymorphisms., PMID:36054934
T-bet+ B cells accumulate in adipose tissue and exacerbate metabolic disorder during obesity., PMID:35868310
ABCB1 gene polymorphisms impact the effect of high-dose intravenous methylprednisolone therapy on optic neuritis associated with AQP4-IgG-positive neuromyelitis optica spectrum disorder., PMID:35488449
Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection., PMID:35446923
Transcriptional programming and gene regulation in WC1+ γδ T cell subpopulations., PMID:34959072
Decreased expression of T-cell-associated immune markers predicts poor prognosis in patients with follicular lymphoma., PMID:34837284
Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis., PMID:34762705
Cytotoxic T lymphocyte antigen-4 regulates development of xenogenic graft versus host disease in mice via modulation of host immune responses induced by changes in human T cell engraftment and gene expression., PMID:34487545
CCL17-CCR4 axis contributes to the onset of vitiligo in mice., PMID:34077992
Total Phenolic Fraction (TPF) from Extra Virgin Olive Oil: Induction of apoptotic-like cell death in Leishmania spp. promastigotes and in vivo potential of therapeutic immunomodulation., PMID:33428610
Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders., PMID:33384688
Age-Associated B Cells (ABCs) in the Prognosis, Diagnosis and Therapy of Systemic Lupus Erythematosus (SLE)., PMID:33163863
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is associated with IRF7, BANK1 and TBX21 polymorphisms in two populations., PMID:33065758
Oral Administration of Sargassum horneri Improves the HDM/DNCB-Induced Atopic Dermatitis in NC/Nga Mice., PMID:32824648
PD-1 antibody and ruxolitinib enhances graft-versus-lymphoma effect without increasing acute graft-versus-host disease in mice., PMID:32805756
Reproducing the molecular subclassification of peripheral T-cell lymphoma-NOS by immunohistochemistry., PMID:31562134
Dysregulation of Akt-FOXO1 Pathway Leads to Dysfunction of Regulatory T Cells in Patients with Psoriasis., PMID:30998985
Age (autoimmunity) associated B cells (ABCs) and their relatives., PMID:30388513
Clinical significance of CD161+CD4+ T cells in the development of chronic antibody-mediated rejection in kidney transplant recipients., PMID:30011312
Enhancement of Immunoregulatory Function of Modified Bone Marrow Mesenchymal Stem Cells by Targeting SOCS1., PMID:29854745
Distinct In Vitro T-Helper 17 Differentiation Capacity of Peripheral Naive T Cells in Rheumatoid and Psoriatic Arthritis., PMID:29670615
Immune molecular profiling of whole blood drawn from a non-human primate cardiac xenograft model treated with anti-CD154 monoclonal antibodies., PMID:29582477
A novel in vivo adjuvant activity of kaempferol: enhanced Tbx-21, GATA-3 expression and peritoneal CD11c+MHCII+ dendritic cell infiltration., PMID:29486619
Association of IL-28B, TBX21 gene polymorphisms and predictors of virological response for chronic hepatitis C., PMID:29399747
Sodium chloride inhibits IFN-γ, but not IL-4, production by invariant NKT cells., PMID:29345057
Small-Molecule Inhibition of PD-1 Transcription Is an Effective Alternative to Antibody Blockade in Cancer Therapy., PMID:29055015
A candidate gene approach to study nematode resistance traits in naturally infected sheep., PMID:28807314
Quercetin exhibits adjuvant activity by enhancing Th2 immune response in ovalbumin immunized mice., PMID:28380410
The Induction and Maintenance of Transplant Tolerance Engages Both Regulatory and Anergic CD4+ T cells., PMID:28321218
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity., PMID:28228602
Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4+ T Cells., PMID:27833268
Human circulating group 2 innate lymphoid cells can express CD154 and promote IgE production., PMID:27576126
Molecular immunology profiles of monkeys following xenografting with the islets and heart of α-1,3-galactosyltransferase knockout pigs., PMID:27511303
The leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genes., PMID:27501956
Variations in T Cell Transcription Factor Sequence and Expression Associated with Resistance to the Sheep Nematode Teladorsagia circumcincta., PMID:26890074
Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD., PMID:26887440
The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies., PMID:26762769
Deletion of collapsin response mediator protein 4 results in abnormal layer thickness and elongation of mitral cell apical dendrites in the neonatal olfactory bulb., PMID:26739921
Short communication: Cytokine profiles from blood mononuclear cells of dairy cows classified with divergent immune response phenotypes., PMID:26723120
Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12., PMID:26470881
For research use only. Not for human or drug use.
