Catalog No.
YHD05101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn21-Cys144
Predicted molecular weight
16.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14555
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phosphatidylcholine 2-acylhydrolase 2A, NPS-PLA2, RASF-A, Non-pancreatic secretory phospholipase A2, Group IIA phospholipase A2, GIIC sPLA2, PLA2L, PLA2G2A, PLA2B, Phospholipase A2, membrane associated
Identification of potential human targets for epigallocatechin gallate through a novel protein binding site screening approach., PMID:40512223
Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis., PMID:40473047
Metabolomics and proteomics analyses reveal the role of the glycerophospholipid metabolism pathway in unexplained recurrent spontaneous abortion., PMID:40321821
Integrating Metabolomics and Network Analyses to Explore Mechanisms of Geum japonicum var. chinense Against Pulmonary Fibrosis: Involvement of Arachidonic Acid Metabolic Pathway., PMID:40003932
Casein Glycomacropeptide Regulates Gene Expression in Intestinal Epithelial Cells: Effect of Simulated Gastrointestinal Digestion and Peptide Microencapsulation., PMID:39921639
Regulation of Paneth cell-specific genes in COVID-19 patients and SARS-CoV-2-infected mice by quantification of mRNA from exfoliated cells in stool samples., PMID:39738327
Proteomic profiling reveals the significance of lipid metabolism in small cell lung cancer recurrence and metastasis., PMID:39707352
Identification and validation of cigarette smoking-related genes in predicting prostate cancer development through bioinformatic analysis and experiments., PMID:39625524
Circulating mitochondria carrying cGAS promote endothelial Secreted group IIA phospholipase A2-mediated neuroinflammation through activating astroglial/microglial Integrin-alphavbeta3 in subfornical organ to augment central sympathetic overdrive in heart failure rats., PMID:39586230
Ergothioneine Ameliorates Liver Fibrosis by Inhibiting Glycerophospholipids Metabolism and TGF-β/Smads Signaling Pathway: Based on Metabonomics and Network Pharmacology., PMID:39579000
Integrated Metabolomics and Network Pharmacology Study on the Mechanism of Rehmanniae radix Extract for Treating Thrombosis., PMID:39497835
High expression of PLA2G2A in fibroblasts plays a crucial role in the early progression of carotid atherosclerosis., PMID:39449149
STUB1-mediated K63-linked ubiquitination of UHRF1 promotes the progression of cholangiocarcinoma by maintaining DNA hypermethylation of PLA2G2A., PMID:39267107
Inhibitory Effect and Mechanism of Epigallocatechin Gallate on the Differentiation of 3T3-L1 Preadipocytes., PMID:39186142
Association between thermogenic brown fat and genes under positive natural selection in circumpolar populations., PMID:39160621
Identification of an Allele-Specific Transcription Factor Binding Interaction that May Regulate PLA2G2A Gene Expression., PMID:39081667
Identification of senescence related hub genes and potential therapeutic compounds for dilated cardiomyopathy via comprehensive transcriptome analysis., PMID:39029429
Single-cell transcriptomics analysis of bullous pemphigoid unveils immune-stromal crosstalk in type 2 inflammatory disease., PMID:39009587
Identification and experimental validation of immune-related gene PPARG is involved in ulcerative colitis., PMID:38880160
SELENOI Functions as a Key Modulator of Ferroptosis Pathway in Colitis and Colorectal Cancer., PMID:38757622
Potential Molecular Markers for Cholecystic Inflammation-Induced Carcinogenesis Based on RNA-Seq Gene Screening., PMID:38716548
Loss of NLRP6 expression increases the severity of intestinal injury after syngeneic hematopoietic stem cell transplantation., PMID:38607553
Inhibition of RXRA-mediated PLA2G2A improves delirium in COPD mice by regulating endoplasmic reticulum stress pathway and inhibiting cell apoptosis., PMID:38372090
Evaluating the efficacy and mechanisms of Hua-Zhuo-Ning-Fu-Decoction on psoriasis using integrated bioinformatics analysis and metabolomics., PMID:38316220
Metabolomic and Immunologic Discriminators of MIS-C at Emergency Room Presentation., PMID:38293197
Metabolomic insights into the therapeutic mechanisms of costus (Saussurea costus (Falc.) Lipsch.) root extract in propylthiouracil-induced hypothyroidism rat model., PMID:38253277
IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids., PMID:38232700
Stachydrine represses the proliferation and enhances cell cycle arrest and apoptosis of breast cancer cells via PLA2G2A/DCN axis., PMID:38230769
Anti-obesity effects of mulberry leaf extracts on female high-fat diet-induced obesity: Modulation of white adipose tissue, gut microbiota, and metabolic markers., PMID:38225139
Identification of an allele-specific transcription factor binding interaction that regulates PLA2G2A gene expression., PMID:38168258
Single-cell Transcriptomic Analysis Reveals an Immunosuppressive Network Between POSTN CAFs and ACKR1 ECs in TKI-resistant Lung Cancer., PMID:38151287
Beyond the Rhythm: In Silico Identification of Key Genes and Therapeutic Targets in Atrial Fibrillation., PMID:37893006
Identification and immunological characterization of PLA2G2A and cell death-associated molecular clusters in idiopathic pulmonary fibrosis., PMID:37673297
Lactiplantibacillus plantarum L47 and inulin alleviate enterotoxigenic Escherichia coli induced ileal inflammation in piglets by upregulating the levels of α-linolenic acid and 12,13-epoxyoctadecenoic acid., PMID:37635926
Mechanistic exploration of Yiqi Liangxue Shengji prescription on restenosis after balloon injury by integrating metabolomics with network pharmacology., PMID:37602438
PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke., PMID:37490917
A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids., PMID:37476158
Altered distribution of fatty acid exerting lipid metabolism and transport at the maternal-fetal interface in fetal growth restriction., PMID:37406553
Primary testicular lymphoma demonstrates overexpression of the Wilms tumor 1 gene and different mRNA and miRNA expression profiles compared to nodal diffuse large B-cell lymphoma., PMID:37291944
Proteomic profiling and functional characterization of serum-derived extracellular vesicles in the mucinous and non-mucinous colon adenocarcinoma., PMID:37204515
The activities and mechanisms of intestinal microbiota metabolites of TCM herbal ingredients could be illustrated by a strategy integrating spectrum-effects, network pharmacology, metabolomics and molecular docking analysis: Platycodin D as an example., PMID:37094423
Study on mechanism of hepatoprotective effect of Chrysanthemum morifolium Ramat. based on metabolomics with network analysis and network pharmacology., PMID:37059010
Cellular Distribution of Secreted Phospholipase A2 in Lungs of IPF Patients and Its Inhibition in Bleomycin-Induced Pulmonary Fibrosis in Mice., PMID:37048117
Lipidomics of the erythrocyte membrane and network pharmacology to explore the mechanism of mangiferin from Anemarrhenae rhizoma in treating type 2 diabetes mellitus rats., PMID:37044004
PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice., PMID:37030630
PLA2G2A+ cancer-associated fibroblasts mediate pancreatic cancer immune escape via impeding antitumor immune response of CD8+ cytotoxic T cells., PMID:36796670
FABP4 in Paneth cells regulates antimicrobial protein expression to reprogram gut microbiota., PMID:36519446
PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation., PMID:36233022
Upregulation of Metallothionein 1 G (MT1G) Negatively Regulates Ferroptosis in Clear Cell Renal Cell Carcinoma by Reducing Glutathione Consumption., PMID:36204178
Multimodal regulation of the osteoclastogenesis process by secreted group IIA phospholipase A2., PMID:36105351
For research use only. Not for human or drug use.
