Catalog No.
RHN68601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Fat facets protein-related, X-linked, Fat facets in mammals, Ubiquitin thioesterase FAF-X, USP9X, USP9, hFAM, Deubiquitinating enzyme FAF-X, Ubiquitin-specific-processing protease FAF-X, Probable ubiquitin carboxyl-terminal hydrolase FAF-X, FAM, DFFRX, Ubiquitin-specific protease 9, X chromosome
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q93008
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2Q32
ERK-USP9X-coupled regulation of thymidine kinase 1 promotes both its enzyme activity-dependent and its enzyme activity-independent functions for tumor growth., PMID:39824978
Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition., PMID:37260183
The deubiquitylase USP9X controls ribosomal stalling., PMID:33507233
USP9X deubiquitinates ALDH1A3 and maintains mesenchymal identity in glioblastoma stem cells., PMID:30958800
The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation., PMID:27203743
Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity., PMID:26936881
Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction., PMID:26769899
β-catenin is regulated by USP9x and mediates resistance to TRAIL-induced apoptosis in breast cancer., PMID:26717875
Methylation analysis of histone H4K12ac-associated promoters in sperm of healthy donors and subfertile patients., PMID:25806092
ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination., PMID:20406983
The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X., PMID:17038327
Doublecortin interacts with the ubiquitin protease DFFRX, which associates with microtubules in neuronal processes., PMID:15607950
The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme., PMID:9722616
For research use only. Not for human or drug use.
