Catalog No.
RHN68301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
COP9 signalosome complex subunit 5, JAB1, Signalosome subunit 5, CSN5, COPS5, Jun activation domain-binding protein 1, SGN5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92905
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2Q28
Integrative analysis of serum proteomics and transcriptomics in hepatitis C., PMID:40082995
Interaction between SCP3 and JAB1 Confers Cancer Therapeutic Resistance and Stem-like Properties through EGF Expression., PMID:34445562
S100A7 in Psoriasis: Immunodetection and Activation by CRISPR technology., PMID:30710307
The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice., PMID:27693579
Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step., PMID:26437402
Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients., PMID:23172669
Huntingtin with an expanded polyglutamine repeat affects the Jab1-p27(Kip1) pathway., PMID:22426400
Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation., PMID:21991377
Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3., PMID:20399188
Overexpression of adenovirus-mediated p27kip1 lacking the Jab1-binding region enhances cytotoxicity and inhibits xenografted human cholangiocarcinoma growth., PMID:19528460
[Molecular mechanism of the inhibitory effect of retinoic acid-induced gene G protein on tumor cell proliferation]., PMID:18353217
Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity., PMID:17310986
Preparation and characterization of monoclonal antibodies against mouse Jab1/CSN5 protein., PMID:17203996
Genetic regulators of large-scale transcriptional signatures in cancer., PMID:16518402
Jun activation domain-binding protein 1 is required for mitotic checkpoint activation via its involvement in hyperphosphorylation of 53BP1., PMID:16187115
Decreased survival of mosquito cells after stable transfection with a Drosophila ecdysteroid response element: possible involvement of a 40 kDa DNA binding protein., PMID:15455055
JAB1 participates in unfolded protein responses by association and dissociation with IRE1., PMID:15234121
Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity., PMID:10766246
Characterization of the mouse JAB1 cDNA and protein., PMID:10721695
For research use only. Not for human or drug use.
