Catalog No.
YHD03501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr17-Asn230
Predicted molecular weight
27.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14207
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FBP, FOLR2, Folate receptor beta, Placental folate-binding protein, Folate receptor, fetal/placental, FR-beta, Folate receptor 2
Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on cardiometabolic health., PMID:40225784
Unveiling the key mechanisms of FOLR2+ macrophage-mediated antitumor immunity in breast cancer using integrated single-cell RNA sequencing and bulk RNA sequencing., PMID:40045365
Computational insights into maternal environmental pollutants and folate pathway regulation., PMID:39732410
Proteome-wide reverse molecular docking reveals folic acid receptor as a mediator of PFAS-induced neurodevelopmental toxicity., PMID:39605555
Visualizing the spatial organization of monocytes, interstitial macrophages, and tissue-specific macrophages in situ., PMID:39395172
Defining Alzheimer's Disease through Proteomic CSF Profiling., PMID:39373095
Progesterone promotes CXCl2-dependent vaginal neutrophil killing by activating cervical resident macrophage-neutrophil crosstalk., PMID:39298265
Folate Receptor β (FRβ) Expression on Myeloid Cells and the Impact of Reticuloendothelial System on Folate-Functionalized Nanoparticles' Biodistribution in Cancer., PMID:39105761
Single-cell resolution characterization of myeloid-derived cell states with implication in cancer outcome., PMID:38972873
Expression of the Folate Receptor Proteins FOLR1 and FOLR2 in Correlation With Clinicopathological Variables of Gastric Cancer., PMID:38915965
Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension., PMID:38779688
Deciphering the spatial landscape and plasticity of immunosuppressive fibroblasts in breast cancer., PMID:38561380
CD163-Mediated Small-Vessel Injury in Alzheimer's Disease: An Exploration from Neuroimaging to Transcriptomics., PMID:38396970
A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer., PMID:38307032
WNT-dependent interaction between inflammatory fibroblasts and FOLR2+ macrophages promotes fibrosis in chronic kidney disease., PMID:38272907
Folate receptor overexpression induces toxicity in a diet-dependent manner in C. elegans., PMID:38212621
Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy., PMID:38168935
microRNA-622 upregulates cell cycle process by targeting FOLR2 to promote CRC proliferation., PMID:38166756
Mirvetuximab soravtansine-gynx: first antibody/antigen-drug conjugate (ADC) in advanced or recurrent ovarian cancer., PMID:38101816
Recent Advances in Folates and Autoantibodies against Folate Receptors in Early Pregnancy and Miscarriage., PMID:38068740
SPP1+ TAM subpopulations in tumor microenvironment promote intravasation and metastasis of head and neck squamous cell carcinoma., PMID:38052857
Mutational analysis of FOLR1 and FOLR2 genes in children with Myelomeningocele., PMID:37883728
Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma., PMID:37532692
Functional Annotation and Gene Set Analysis of Gastric Cancer Risk Loci in a Korean Population., PMID:37340842
Roux-en-Y gastric bypass affects the expression of genes related to the intestinal folate metabolism pathway in obese women., PMID:37224573
FDA Approval Summary: Mirvetuximab Soravtansine-Gynx for FRα-Positive, Platinum-Resistant Ovarian Cancer., PMID:37212825
scRNA-seq reveals aging-related immune cell types and regulators in vaginal wall from elderly women with pelvic organ prolapse., PMID:36891295
Single-cell RNA sequencing reveals unique monocyte-derived interstitial macrophage subsets during lipopolysaccharide-induced acute lung inflammation., PMID:36852927
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity., PMID:36496458
Elevated expression of receptors for EGF, PDGF, transferrin and folate within murine and human lupus nephritis kidneys., PMID:36396012
Identification of a six-gene prognostic signature for bladder cancer associated macrophage., PMID:36275756
Stage specific gene expression of folate mediated one-carbon metabolism enzymes and transporters in buffalo oocytes and pre-implantation embryos., PMID:36244619
Integrated single-cell RNA-seq analysis identifies immune heterogeneity associated with KRAS/TP53 mutation status and tumor-sideness in colorectal cancers., PMID:36172359
A Population of TIM4+FOLR2+ Macrophages Localized in Tertiary Lymphoid Structures Correlates to an Active Immune Infiltrate Across Several Cancer Types., PMID:36122412
Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis., PMID:35967299
ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF., PMID:35820705
Integrated proteomics and metabolomics analysis reveals hubs protein and network alterations in myasthenia gravis., PMID:35802752
Global DNA hypomethylation of colorectal tumours detected in tissue and liquid biopsies may be related to decreased methyl-donor content., PMID:35655145
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state., PMID:35587037
Association of periconceptional folate supplements and FOLR1 and FOLR2 gene polymorphisms with risk of congenital heart disease in offspring: A hospital-based case-control study., PMID:35545363
FOLR2+ Macrophages Are Associated with T-cell Infiltration and Improved Prognosis., PMID:35394484
Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer., PMID:35325594
Association of polymorphisms of FOLR1 gene and FOLR2 gene and maternal folic acid supplementation with risk of ventricular septal defect: a case-control study., PMID:35273364
Folate Receptor Expression by Human Monocyte-Derived Macrophage Subtypes and Effects of Corticosteroids., PMID:35255727
Folate Receptor Beta for Macrophage Imaging in Rheumatoid Arthritis., PMID:35185910
Folate receptor-1 is vital for developmental competence of goat embryos., PMID:35122705
Emerging roles for folate receptor FOLR1 in signaling and cancer., PMID:35094917
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles., PMID:34995099
Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes., PMID:34755134
The Ontogeny and Function of Placental Macrophages., PMID:34745147
For research use only. Not for human or drug use.
