Anti-PRPF31 Antibody (R2P66)

Catalog No.

RHN64702

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000

Target

hPrp31, Pre-mRNA-processing factor 31, Protein 61K, U4/U6 small nuclear ribonucleoprotein Prp31, U4/U6 snRNP 61 kDa protein, PRPF31, Serologically defined breast cancer antigen NY-BR-99, PRP31

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8WWY3

Applications

FCM, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2P66

PRPF31 interacts with PRPH2 confirmed by co-immunoprecipitation and co-localization., PMID:36088804

Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation., PMID:30475206

CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31., PMID:21385873

Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells., PMID:15659613

Expression of PRPF31 mRNA in patients with autosomal dominant retinitis pigmentosa: a molecular clue for incomplete penetrance?, PMID:14507862

Document Download

Anti-PRPF31 Antibody (R2P66).pdf