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Anti-DTL Antibody (R2P48)

Catalog #:   RHN63701 Specific References (41) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, WB
Accession: Q9NZJ0
Overview

Catalog No.

RHN63701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:100, WB: 1:500-1:1000

Target

DDB1- and CUL4-associated factor 2, DCAF2, CDW1, Lethal(2) denticleless protein homolog, RAMP, DTL, Retinoic acid-regulated nuclear matrix-associated protein, L2DTL, Denticleless protein homolog, CDT2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NZJ0

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2P48

Data Image
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human lung cancer using CDT2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of CDT2 in Hela lysates using CDT2 antibody.
References

Final results of urelumab, an anti-CD137 agonist monoclonal antibody, in combination with cetuximab or nivolumab in patients with advanced solid tumors., PMID:38458639

A Case of Diffuse Thyroid Lipomatosis With Amyloid Deposits Presenting With Thyrotoxicosis., PMID:38440128

Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032)., PMID:38316517

A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma., PMID:37339979

Pembrolizumab in Asian patients with microsatellite-instability-high/mismatch-repair-deficient colorectal cancer., PMID:36369901

COVID-19 infection after two doses of SARS-CoV-2 mRNA vaccine in multiple sclerosis, AQP4-antibody NMOSD and MOGAD., PMID:35803084

Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study., PMID:35427471

Persistence, effectiveness, and real-world outcomes in psoriasis patients treated with secukinumab in Portugal., PMID:35419886

Identification of RRM2 in peripheral blood mononuclear cells as a novel biomarker for the diagnosis of rheumatoid arthritis., PMID:35200126

Proliferative diabetic retinopathy treated with intravitreal ranibizumab and photocoagulation directed at ischemic retinal areas-A randomized study., PMID:34347216

Improved Performance of ELISA and Immunochromatographic Tests Using a New Chimeric A2-Based Protein for Human Visceral Leishmaniasis Diagnosis., PMID:34007852

Health-related quality of life in patients with microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer treated with first-line pembrolizumab versus chemotherapy (KEYNOTE-177): an open-label, randomised, phase 3 trial., PMID:33812497

DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously., PMID:33514724

Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer., PMID:33264544

Microporous Drug Delivery System for Sustained Anti-VEGF Delivery to the Eye., PMID:32855852

A Phase II Study of Allogeneic GM-CSF-Transfected Pancreatic Tumor Vaccine (GVAX) with Ipilimumab as Maintenance Treatment for Metastatic Pancreatic Cancer., PMID:32591464

Expression of SLC4A11 protein in mouse and rat medulla: a candidate transporter involved in outer medullary ammonia recycling., PMID:31124301

Intravenous tPA (Tissue-Type Plasminogen Activator) in Patients With Acute Ischemic Stroke Taking Non-Vitamin K Antagonist Oral Anticoagulants Preceding Stroke., PMID:30354981

T cell receptor repertoire features associated with survival in immunotherapy-treated pancreatic ductal adenocarcinoma., PMID:29997287

Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye., PMID:28114570

Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial., PMID:27733243

Descending thin limb of the intermediate loop expresses both aquaporin 1 and urea transporter A2 in the mouse kidney., PMID:27091563

NFI-C2 temporal-spatial expression and cellular localization pattern during tooth formation., PMID:26687982

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency., PMID:26028255

Architecture of kangaroo rat inner medulla: segmentation of descending thin limb of Henle's loop., PMID:22237592

Urine concentrating mechanism in the inner medulla of the mammalian kidney: role of three-dimensional architecture., PMID:21054810

Involvement of elevated expression of multiple cell-cycle regulator, DTL/RAMP (denticleless/RA-regulated nuclear matrix associated protein), in the growth of breast cancer cells., PMID:18542055

L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage., PMID:16861906

Three-dimensional architecture of inner medullary vasa recta., PMID:16380456

Ultrastructural localization of UT-A and UT-B in rat kidneys with different hydration status., PMID:16179486

DTL, the Drosophila homolog of PIMT/Tgs1 nuclear receptor coactivator-interacting protein/RNA methyltransferase, has an essential role in development., PMID:15684427

Three-dimensional functional reconstruction of inner medullary thin limbs of Henle's loop., PMID:14519595

Expression of urea transporters in potassium-depleted mouse kidney., PMID:12952854

Expression of urea transporters in the developing rat kidney., PMID:11832436

Decreased osteopontin expression in the rat kidney on a sodium deficient diet., PMID:10731931

First Report of Cucumber Mosaic Cucumovirus Subgroup 1 in South Africa, from Banana with Infectious Chlorosis., PMID:30856783

Expression of aquaporins-1 and -2 during nephrogenesis and in autosomal dominant polycystic kidney disease., PMID:8760258

Expression of osteopontin, a urinary inhibitor of stone mineral crystal growth, in rat kidney., PMID:7643527

Electron microscopic immunohistochemical localization of components of Na+-cotransporters along the rat nephron., PMID:2744009

Serotype specificity of monoclonal antibodies to cucumber mosaic virus., PMID:2705879

Cloning and identification of the H-2Dp gene., PMID:6323309

Datasheet

Document Download

Anti-DTL Antibody (R2P48).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-DTL Antibody (R2P48) [RHN63701]
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