Catalog No.
RHN63301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:1000-1:2000
Target
MLT, Paracaspase, MALT lymphoma-associated translocation, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, MALT1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UDY8
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2P43
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection., PMID:39082968
PRRSV utilizes MALT1-regulated autophagy flux to switch virus spread and reserve., PMID:39081059
Endoscopic ultrasound-guided fine needle biopsy diagnosis of circumferentially extraluminal mucosa-associated lymphoid tissue lymphoma in the transverse colon: a case report., PMID:38607542
Tumor Intrinsic Subtypes and Gene Expression Signatures in Early-Stage ERBB2/HER2-Positive Breast Cancer: A Pooled Analysis of CALGB 40601, NeoALTTO, and NSABP B-41 Trials., PMID:38546612
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity., PMID:37988467
Clinical relevance of molecular aspects in extranodal marginal zone lymphoma: a critical appraisal., PMID:37389189
Novel agents in relapsed/refractory diffuse large B-cell lymphoma., PMID:37294966
Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer., PMID:37214210
MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas., PMID:36922488
Combining precision oncology and immunotherapy by targeting the MALT1 protease., PMID:36270731
MALT1 reflects inflammatory cytokines, disease activity, and its chronological change could estimate treatment response to infliximab in Crohn's disease patients., PMID:36036788
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 in rheumatoid arthritis: Longitudinal change after treatment and correlation with treatment efficacy of tumor necrosis factor inhibitors., PMID:35500150
Phosphorylation of serine-893 in CARD11 suppresses the formation and activity of the CARD11-BCL10-MALT1 complex in T and B cells., PMID:35230873
Combined detection of lymphocyte clonality and MALT1 translocations in bronchoalveolar lavage fluid for diagnosing pulmonary lymphomas., PMID:34873224
Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency., PMID:33872653
Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway., PMID:33329596
Gastric MALT Lymphoma with Biclonal Gammopathy and Bone Marrow Involvement Mimicking Multiple Myeloma., PMID:33031697
A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis., PMID:32870913
Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL., PMID:32785655
MALT1 Protease Plays a Dual Role in the Allergic Response by Acting in Both Mast Cells and Endothelial Cells., PMID:32213560
Requirement of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor-Induced Arthritis, but Not Fcγ Receptor-Mediated Platelet Elimination, in Mice., PMID:31943941
MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells., PMID:31644910
MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging., PMID:31632405
Primary Low-Grade B-Cell Lymphoma of Skull With Translocation Between Immunoglobulin and Interferon Regulatory Factor 4 Genes., PMID:31631721
Deletion of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis., PMID:31259485
Identification of genetic biomarkers for alloimmunization in sickle cell disease., PMID:31168801
Novel MALT1 Mutation Linked to Immunodeficiency, Immune Dysregulation, and an Abnormal T Cell Receptor Repertoire., PMID:31037583
The MALT1 locus and peanut avoidance in the risk for peanut allergy., PMID:30825465
[The complex morphologic diagnostic of marginal zone lymphoma.]., PMID:30802397
[MALT lymphoma accompanied by elevated serum IgM levels mimicking Waldenström's macroglobulinemia]., PMID:30626796
Glutaminolysis Mediated by MALT1 Protease Activity Facilitates PD-L1 Expression on ABC-DLBCL Cells and Contributes to Their Immune Evasion., PMID:30619766
Epstein-Barr virus microRNAs regulate B cell receptor signal transduction and lytic reactivation., PMID:30615681
Malt1 inactivation attenuates experimental colitis through the regulation of Th17 and Th1/17 cells., PMID:30564895
Primary extranodal diffuse large B-cell lymphomas: Many sites, many entities? Clinico-pathological, immunohistochemical and cytogenetic study of 106 cases., PMID:30553470
Ubiquitination and phosphorylation of the CARD11-BCL10-MALT1 signalosome in T cells., PMID:30514565
Simulation of the Dynamics of Primary Immunodeficiencies in B Cells., PMID:30116248
Posttranscriptional Gene Regulation of T Follicular Helper Cells by RNA-Binding Proteins and microRNAs., PMID:30108596
Pulmonary extranodal marginal zone lymphoma that presented with macroglobulinemia and marked plasmacytic cell proliferation carrying the t(14;18)(q32;q21)/MALT1-immunoglobulin heavy-chain fusion gene in pleural fluid., PMID:30089750
Autocleavage of the paracaspase MALT1 at Arg-781 attenuates NF-κB signaling and regulates the growth of activated B-cell like diffuse large B-cell lymphoma cells., PMID:29953499
A multiprotein supercomplex controlling oncogenic signalling in lymphoma., PMID:29925955
MALT1 Controls Attenuated Rabies Virus by Inducing Early Inflammation and T Cell Activation in the Brain., PMID:29367251
Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9., PMID:28130494
Differing Requirements for MALT1 Function in Peripheral B Cell Survival and Differentiation., PMID:28031341
B-cell receptor-driven MALT1 activity regulates MYC signaling in mantle cell lymphoma., PMID:27864294
Cellular-level characterization of B cells infiltrating pulmonary MALT lymphoma tissues., PMID:27600807
MALT lymphoma: A paradigm of NF-κB dysregulation., PMID:27452667
Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas., PMID:27356265
Primary Endometrial Marginal Zone Lymphoma (MALT Lymphoma): A Unique Clinicopathologic Entity., PMID:27340748
Mechanisms of NF-κB deregulation in lymphoid malignancies., PMID:27262792
For research use only. Not for human or drug use.
