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Anti-SIN3A Antibody (R2P33)

Catalog #:   RHN62701 Specific References (20) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, IHC, WB
Accession: Q96ST3
Overview

Catalog No.

RHN62701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

SIN3A, Transcriptional corepressor Sin3a, Histone deacetylase complex subunit Sin3a, Paired amphipathic helix protein Sin3a

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q96ST3

Applications

FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2P33

Data Image
  • Western blot
    Western blot analysis of mSin3A expression in (1) K562 cell lysate; (2) RAW 264.7 cell lysate.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
References

Ambiguity about Splicing Factor 3b Subunit 3 (SF3B3) and Sin3A Associated Protein 130 (SAP130)., PMID:33800128

Histone deacetylase (Rpd3) regulates Drosophila early brain development via regulation of Tailless., PMID:32873153

The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy., PMID:32482755

Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma., PMID:30617194

Microglial Mincle receptor in the PVN contributes to sympathetic hyperactivity in acute myocardial infarction rat., PMID:30353660

Expression Analysis of p16, c-Myc, and mSin3A in Non-small Cell Lung Cancer by Computer Aided Scoring and Analysis (CASA)., PMID:26118188

Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression., PMID:25921304

Escape mechanisms from antibody therapy to lymphoma cells: downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation., PMID:19769942

Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity., PMID:18316480

Histone deacetylase 1 phosphorylation at S421 and S423 is constitutive in vivo, but dispensable in vitro., PMID:17643391

mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival., PMID:15998811

Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery., PMID:15148359

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns., PMID:14519686

Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines., PMID:12634383

REST repression of neuronal genes requires components of the hSWI.SNF complex., PMID:12192000

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA., PMID:11884454

A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1., PMID:11013263

The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex., PMID:10734093

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex., PMID:10471499

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor., PMID:10049357

Datasheet

Document Download

Anti-SIN3A Antibody (R2P33).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-SIN3A Antibody (R2P33) [RHN62701]
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