Catalog No.
RHN62401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Double parked homolog, DNA replication factor Cdt1, CDT1, DUP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H211
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2P30
HER2 as a potential therapeutic target on quiescent prostate cancer cells., PMID:36805918
ACACB is a novel metabolism-related biomarker in the prediction of response to cetuximab therapy inmetastatic colorectal cancer., PMID:36111743
CelloSelect - A synthetic cellobiose metabolic pathway for selection of stable transgenic CHO cell lines., PMID:35007751
Proteomic and immunomic analysis of Schistosoma mekongi egg proteins., PMID:30009810
The Analysis of Cell Cycle-related Proteins in Ovarian Clear Cell Carcinoma Versus High-grade Serous Carcinoma., PMID:29019869
Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma., PMID:25940995
Imaging analysis of cell cycle-dependent degradation of Cdt1 in mammalian cells., PMID:24906323
Immunohistochemistry-based cell cycle detection (iCCD): a novel system to visualize cell kinetics on formalin-fixed paraffin-embedded tissues., PMID:22498826
Live-cell imaging visualizes frequent mitotic skipping during senescence-like growth arrest in mammary carcinoma cells exposed to ionizing radiation., PMID:22365624
Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor., PMID:22072567
Geminin, Ki67, and minichromosome maintenance 2 in gastric hyperplastic polyps, adenomas, and intestinal-type carcinomas: pathobiological significance., PMID:20820987
Replication origins are already licensed in G1 arrested unfertilized sea urchin eggs., PMID:20153311
Increased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformation., PMID:20064876
Immunohistochemical expression of geminin in colorectal cancer: Implication of prognostic significance., PMID:19360293
Analysis of re-replication from deregulated origin licensing by DNA fiber spreading., PMID:19010964
Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle., PMID:17533120
Developmentally regulated histone modifications in Drosophila follicle cells: initiation of gene amplification is associated with histone H3 and H4 hyperacetylation and H1 phosphorylation., PMID:17219175
The minimal replicator element of the Kaposi's sarcoma-associated herpesvirus terminal repeat supports replication in a semiconservative and cell-cycle-dependent manner., PMID:17151118
L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage., PMID:16861906
Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts., PMID:15668171
Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1., PMID:15466399
DNA replication licensing and cell cycle kinetics of oligodendroglial tumours., PMID:15199392
Expression of the cytolethal distending toxin in a geographically diverse collection of Haemophilus ducreyi clinical isolates., PMID:12902578
Two novel mutations in the gene encoding thyroxine-binding globulin (TBG) as a cause of complete TBG deficiency in Taiwan., PMID:12641622
Essential role of human CDT1 in DNA replication and chromatin licensing., PMID:11896191
Redundant control of rereplication in fission yeast., PMID:11606752
Immunochemical identification of the pssA gene product as phosphatidylserine synthase I of Chinese hamster ovary cells., PMID:8898108
DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast., PMID:8537450
For research use only. Not for human or drug use.
