Catalog No.
RHN61201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
MEKK 3, MAP3K3, MEK kinase 3, MEKK3, MAPK/ERK kinase kinase 3, Mitogen-activated protein kinase kinase kinase 3, MAPKKK3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q99759
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2P15
Expression and prognostic role of MEKK3 and pERK in patients with renal clear cell carcinoma., PMID:25824786
Brominated flame retardants, tetrabromobisphenol A and hexabromocyclododecane, activate mitogen-activated protein kinases (MAPKs) in human natural killer cells., PMID:25341744
TGFβ2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion., PMID:20633555
Phosphorylation of Thr-516 and Ser-520 in the kinase activation loop of MEKK3 is required for lysophosphatidic acid-mediated optimal IkappaB kinase beta (IKKbeta)/nuclear factor-kappaB (NF-kappaB) activation., PMID:20068038
Proteomic identification of the cerebral cavernous malformation signaling complex., PMID:17900104
Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation., PMID:17214902
Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation., PMID:16407301
Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R., PMID:12393391
Phosphorylation of the stress-activated protein kinase, MEKK3, at serine 166., PMID:12392720
For research use only. Not for human or drug use.
