Catalog No.
RHN60601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Verprolin homology domain-containing protein 2, WAVE2, WASF2, Protein WAVE-2, Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y6W5
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2P08
CD147 regulates cancer migration via direct interaction with Annexin A2 and DOCK3-β-catenin-WAVE2 signaling., PMID:26716413
Effect of omega-3 polyunsaturated fatty acids on the cytoskeleton: an open-label intervention study., PMID:25971815
Decreased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 may be involved in the development of pre-eclampsia., PMID:24125947
Degradation of actin nucleators affects cortical polarity of aged mouse oocytes., PMID:22306711
WAVE2 regulates meiotic spindle stability, peripheral positioning and polar body emission in mouse oocytes., PMID:21543895
Nonmuscle myosin IIA is required for lamellipodia formation through binding to WAVE2 and phosphatidylinositol 3,4,5-triphosphate., PMID:21184743
Overexpression of HER2 signaling to WAVE2-Arp2/3 complex activates MMP-independent migration in breast cancer., PMID:20419393
A major role for Scar/WAVE-1 downstream of GPVI in platelets., PMID:17319906
MRP-1/CD9 gene transduction regulates the actin cytoskeleton through the downregulation of WAVE2., PMID:16682943
A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages., PMID:16280551
WAVE/Scars in platelets., PMID:15280206
IRSp53 is colocalised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of Mena., PMID:12734400
For research use only. Not for human or drug use.
