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Anti-PHLDA1 Antibody (R2N68)

Catalog #:   RHN29501 Specific References (16) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: Q8WV24
Overview

Catalog No.

RHN29501

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000

Target

Proline- and histidine-rich protein, T-cell death-associated gene 51 protein, Pleckstrin homology-like domain family A member 1, PQR protein, Apoptosis-associated nuclear protein, PHRIP, PHLDA1, Proline- and glutamine-rich protein, TDAG51, PQ-rich protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8WV24

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2N68

Data Image
  • Western blot
    Western blot analysis of PHLDA1 in A375 lysates using PHLDA1 antibody.
References

Silencing of the PHLDA1 leads to global proteome changes and differentiation pathways of human neuroblastoma cells., PMID:38495105

Androgen receptor expression in epidermal and adnexal tumours., PMID:33478823

Systems analysis identifies potential target genes to overcome cetuximab resistance in colorectal cancer cells., PMID:30719834

Lewis(y) antigen-mediated positive feedback loop induces and promotes chemotherapeutic resistance in ovarian cancer., PMID:30066907

GD2 ganglioside-binding antibody 14G2a and specific aurora A kinase inhibitor MK-5108 induce autophagy in IMR-32 neuroblastoma cells., PMID:30027525

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer., PMID:29490281

Downregulation of the PHLDA1 gene in IMR-32 neuroblastoma cells increases levels of Aurora A, TRKB and affects proteins involved in apoptosis and autophagy pathways., PMID:27278006

Primitive follicular induction in molluscum contagiosum., PMID:26265178

Gene expression markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance)., PMID:25520391

Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors., PMID:25473223

Modulation of stemness in a human normal intestinal epithelial crypt cell line by activation of the WNT signaling pathway., PMID:24534551

Targeting GD2 ganglioside and aurora A kinase as a dual strategy leading to cell death in cultures of human neuroblastoma cells., PMID:23962557

TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia., PMID:12738777

Identification of the human PHLDA1/TDAG51 gene: down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation., PMID:12384558

A proline- and glutamine-rich protein promotes apoptosis in neuronal cells., PMID:10428057

Protein kinase C regulates Fas (CD95/APO-1) expression., PMID:9725212

Datasheet

Document Download

Anti-PHLDA1 Antibody (R2N68).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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For research use only. Not for human or drug use.

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Anti-PHLDA1 Antibody (R2N68) [RHN29501]
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