Catalog No.
RHN07002
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
hFz8, Frizzled-8, Fz-8, FZD8
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H461
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N48
Identification and functional validation of FZD8-specific antibodies., PMID:37926311
WNT2-SOX4 positive feedback loop promotes chemoresistance and tumorigenesis by inducing stem-cell like properties in gastric cancer., PMID:37634009
Canonical Wnt signaling activation by chimeric antigen receptors for efficient cardiac differentiation from mouse embryonic stem cells., PMID:36765434
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo., PMID:32818433
RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma., PMID:31286874
A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties., PMID:30183492
Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors., PMID:27869803
Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28., PMID:25172549
Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences., PMID:18799682
Activation of Wnt/beta-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia., PMID:17614820
The role of Xenopus frizzled-8 in pronephric development., PMID:15358202
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled., PMID:11520064
For research use only. Not for human or drug use.
