Catalog No.
RHM01101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
HLA-DRB4, HLA class II histocompatibility antigen, DR beta 4 chain, MHC class II antigen DRB4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P13762
Applications
FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N40
Effects of Teprotumumab and Role of Human Leukocyte Antigens Markers in Patients With Thyroid Eye Disease., PMID:39187158
High resolution HLA genotyping with third generation sequencing technology-A multicentre study., PMID:39132735
Oral Insulin Delay of Stage 3 Type 1 Diabetes Revisited in HLA DR4-DQ8 Participants in the TrialNet Oral Insulin Prevention Trial (TN07)., PMID:38949847
High-resolution HLA sequencing and hypocretin receptor 2 autoantibodies in narcolepsy type 1 and type 2., PMID:38898624
Utilizing the Banana S-Adenosyl-L-Homocysteine Hydrolase Allergen to Identify Cross-Reactive IgE in Ryegrass-, Latex-, and Kiwifruit-Allergic Individuals., PMID:38891986
Class II HLA-DRB4 is a predictive biomarker for survival following immunotherapy in metastatic non-small cell lung cancer., PMID:38172168
High-resolution HLA genotyping in inclusion body myositis refines 8.1 ancestral haplotype association to DRB1*03:01:01 and highlights pathogenic role of arginine-74 of DRβ1 chain., PMID:38043487
HLA-DR4 and DRB4 and COVID-19 vaccination-related ANCA-associated vasculitis: Correspondence., PMID:36156421
HLA-DR4 and DRB4: Potential risk alleles for COVID-19 vaccination-related ANCA-associated vasculitis., PMID:36074724
Sib-pair subgroup familial type 1 diabetes mellitus in children in the state of Qatar., PMID:35802651
Peptides Derived From Mismatched Paternal Human Leukocyte Antigen Predicted to Be Presented by HLA-DRB1, -DRB3/4/5, -DQ, and -DP Induce Child-Specific Antibodies in Pregnant Women., PMID:34992608
Human Leukocyte Antigen Typing with Sequence Specific Oligonucleotides for Renal Transplantation in South Africa., PMID:34758233
The association between juvenile autoimmune hepatitis and HLA-DRB1 alleles: Iraqi tertiary center experience., PMID:34295985
Recurrent secondary graft failure likely due to a DRB4 donor-specific antibody in a patient with aplastic anemia and DRB4 null allele., PMID:34234296
Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Update: Genetic Pathogenesis., PMID:33841406
Comparative analysis of human leucocyte antigen between idiopathic and anti-PD-1 antibody induced isolated adrenocorticotropic hormone deficiency: A pilot study., PMID:31468541
Restricted myeloperoxidase epitopes drive the adaptive immune response in MPO-ANCA vasculitis., PMID:31383567
A reverse-engineering strategy utilizing the integration of single antigen beads and NGS HLA genotypes to detect potential antibody inducing epitopes., PMID:30978444
Pulmonary alveolar proteinosis: An autoimmune disease lacking an HLA association., PMID:30845238
Association of protein tyrosine phosphatase non-receptor type 22 gene functional variant C1858T, HLA-DQ/DR genotypes and autoantibodies with susceptibility to type-1 diabetes mellitus in Kuwaiti Arabs., PMID:29924845
Clinical significance of detecting HLA-DR, 14-3-3η protein and d-dimer in the diagnosis of rheumatoid arthritis., PMID:29856230
Anti-LGI1 encephalitis is strongly associated with HLA-DR7 and HLA-DRB4., PMID:28026046
Subclinical antibody-mediated rejection due to anti-human-leukocyte-antigen-DR53 antibody accompanied by plasma cell-rich acute rejection in a patient with cadaveric kidney transplantation., PMID:26971538
Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes., PMID:26740600
Fetal and neonatal alloimmune thrombocytopenia: predictive factors of intracranial hemorrhage., PMID:26469867
HLA Markers DQ8 and DR53 Are Associated With Lymphocytic Hypophysitis and May Aid in Differential Diagnosis., PMID:26317559
HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study., PMID:26010309
HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease., PMID:25975240
Ex vivo peptide-MHC II tetramer analysis reveals distinct end-differentiation patterns of human pertussis-specific CD4(+) T cells following clinical infection., PMID:25728491
Genetic aspects of anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:25523449
Eosinophilic granulomatosis with polyangiitis: an overview., PMID:25404930
Carbon anhydrase IX specific immune responses in patients with metastatic renal cell carcinoma potentially cured by interleukin-2 based immunotherapy., PMID:23802595
Anti-HLA-A, -B, -DR, -DQB1 and -DQA1 antibodies reactive epitope determination with HLAMatchmaker in multipare awaiting list for heart transplant., PMID:23628396
Study of association between HLA-DR4 and DR53 and autoantibody detection in rheumatoid arthritis., PMID:23537298
Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction., PMID:23454623
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): state of the art., PMID:23330816
The impact of HLA-DRB alleles on the subclass titres of antibodies against citrullinated peptides., PMID:20584722
[An evaluation of HLA class 2 alleles and anti-islet antibodies as evidence for non-autoimmune diabetes in Wolfram syndrome]., PMID:21447263
Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link., PMID:19922436
HLA-DR in Brazilian patients with polyarteritis nodosa (PAN) and microscopic polyangiitis (MPA)., PMID:19597292
Subclinical rejection in stable positive crossmatch kidney transplant patients: incidence and correlations., PMID:19538492
Modulation of antibody response in a sensitized patient with ongoing antibody-mediated injury., PMID:20524322
Anti-cofactor autoantibodies in systemic lupus erythematosus: prevalence, clinical and HLA class II associations., PMID:18569076
Frequency of concurrent autoimmune disorders in patients with autoimmune hepatitis: effect of age, gender, and genetic background., PMID:18223493
Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR,DQ,DP epitopes., PMID:18158123
Antinuclear antibodies and HLA class II alleles in Jamaican patients with systemic lupus erythematosus., PMID:17910142
HLA-DRB4 as a genetic risk factor for Churg-Strauss syndrome., PMID:17763415
HLA markers in familial Lichen sclerosus., PMID:17010173
Humanized transgenic mice expressing HLA DR4-DQ3 haplotype: reconstitution of phenotype and HLA-restricted T-cell responses., PMID:16948641
Defining MHC class II T helper epitopes for WT1 tumor antigen., PMID:16220325
For research use only. Not for human or drug use.
