Catalog No.
RHK83404
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
LTrpC7, LTRPC7, LTrpC-7, TRPM7, Transient receptor potential cation channel subfamily M member 7, CHAK1, Long transient receptor potential channel 7, Channel-kinase 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q96QT4
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N16
TRPM6 in murine kidneys-of targets and antibodies., PMID:40025338
Cardiovascular toxicity of tyrosine kinase inhibitors during cancer treatment: Potential involvement of TRPM7., PMID:36818331
Evidence for the expression of TRPM6 and TRPM7 in cardiomyocytes from all four chamber walls of the human heart., PMID:34326388
The channel-kinase TRPM7 regulates antigen gathering and internalization in B cells., PMID:29871912
Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry., PMID:29445164
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation., PMID:29343440
Hepatocellular differentiation status is characterized by distinct subnuclear localization and form of the chanzyme TRPM7., PMID:28609676
Effects of TRPM7/miR-34a Gene Silencing on Spatial Cognitive Function and Hippocampal Neurogenesis in Mice with Type 1 Diabetes Mellitus., PMID:28185128
TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma., PMID:27629139
Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle., PMID:25820697
TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways., PMID:25192910
Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C γ2 (PLCγ2) using TRPM7-kinase., PMID:22759789
Identification of the phosphorylation sites on intact TRPM7 channels from mammalian cells., PMID:22222377
TRP channel gene expression in the mouse retina., PMID:22037305
TRP expression pattern and the functional importance of TRPC3 in primary human T-cells., PMID:21215279
Functional characterization of transient receptor potential channels in mouse urothelial cells., PMID:20015940
Modulation of TRPM6 and Na(+)/Mg(2+) exchange in mammary epithelial cells in response to variations of magnesium availability., PMID:19890837
Regulation of the novel Mg2+ transporter transient receptor potential melastatin 7 (TRPM7) cation channel by bradykinin in vascular smooth muscle cells., PMID:19145781
[Transient receptor potential melastatin 7 channel protein in human head and neck carcinoma cells and role in cell proliferation]., PMID:18826101
Transient receptor potential cation channels in normal and dystrophic mdx muscle., PMID:18504127
The channel kinases TRPM6 and TRPM7 are functionally nonredundant., PMID:16150690
A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders., PMID:16051700
For research use only. Not for human or drug use.
