Catalog No.
RHK80201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
NPC1L1, Niemann-Pick C1-like protein 1, NPC1-like intracellular cholesterol transporter 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UHC9
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N12
Lipids, lipid-lowering drugs and the risk of herpes zoster: a Mendelian randomization study., PMID:39755897
Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study., PMID:38760735
Established and Emerging Lipid-Lowering Drugs for Primary and Secondary Cardiovascular Prevention., PMID:37486464
Three Musketeers for Lowering Cholesterol: Statins, Ezetimibe and Evolocumab., PMID:32368969
Hepatitis C virus infection and tight junction proteins: The ties that bind., PMID:32268133
Novel milk casein-derived peptides decrease cholesterol micellar solubility and cholesterol intestinal absorption in Caco-2 cells., PMID:32113776
From lipid locus to drug target through human genomics., PMID:29800275
Emerging Targets to Relieve Fat Stress-Induced Liver Diseases: UDCA, Tocotrienol, ω-3 PUFAs, and IgY Targeted NPC1L1 Cholesterol Transporter., PMID:28714405
PCSK9 targets important for lipid metabolism., PMID:28176216
Amelioration of non-alcoholic fatty liver disease with NPC1L1-targeted IgY or n-3 polyunsaturated fatty acids in mice., PMID:27923447
Targeting Viral Entry for Treatment of Hepatitis B and C Virus Infections., PMID:27617925
Quantification of Hepatitis C Virus Cell-to-Cell Spread Using a Stochastic Modeling Approach., PMID:25833046
Resistance and intolerance to statins., PMID:24996502
Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor., PMID:22231557
Lycopene absorption in human intestinal cells and in mice involves scavenger receptor class B type I but not Niemann-Pick C1-like 1., PMID:18641187
Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe., PMID:16177187
Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein., PMID:15777641
For research use only. Not for human or drug use.
