Catalog No.
RHK48802
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:1000-1:2000
Target
Tax1-binding protein 1, TAX1BP1, TRAF6-binding protein, T6BP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q86VP1
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2M26
TAX1BP1-dependent autophagic degradation of STING1 impairs anti-tumor immunity., PMID:40000606
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267
Cleavage of SQSTM1/p62 by the Zika virus protease NS2B3 prevents autophagic degradation of viral NS3 and NS5 proteins., PMID:39128850
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity., PMID:38869076
Decreased TAX1BP1 participates in systemic lupus erythematosus by regulating monocyte/macrophage function., PMID:37465957
TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation., PMID:35266845
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling., PMID:29358708
Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1., PMID:27515252
Immunization of mice with a peptide derived from the HTLV-1 TAX1BP1 protein induces cross-reactive antibodies against aquaporin 4., PMID:26287441
Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling., PMID:25774694
Crystallographic and modelling studies suggest that the SKICH domains from different protein families share a common Ig-like fold but harbour substantial structural variations., PMID:25187058
The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoprotein., PMID:23616667
TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling., PMID:23209807
The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1., PMID:21765415
Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes., PMID:21333492
Gain of GRHL2 is associated with early recurrence of hepatocellular carcinoma., PMID:18752864
Tax1-binding protein 1 is expressed in the retina and interacts with the GABA(C) receptor rho1 subunit., PMID:16999686
For research use only. Not for human or drug use.
