Catalog No.
RHK47201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Vacuolar protein sorting-associated protein 2-2, CHMP2B, CHMP2b, hVps2-2, CHMP2.5, Vps2-2, Charged multivesicular body protein 2b, Chromatin-modifying protein 2b
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UQN3
Applications
FCM, IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2M22
The identification of high-performing antibodies for Charged multivesicular body protein 2b for use in Western Blot, immunoprecipitation and immunofluorescence., PMID:37635943
Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation., PMID:35978952
Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B)., PMID:30414727
ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo., PMID:25008355
Molecular markers for granulovacuolar degeneration are present in rimmed vacuoles., PMID:24312256
Localization of CHMP2B-immunoreactivity in the brainstem of Lewy body disease., PMID:22989140
Cyclin-dependent kinase 5 immunoreactivity for granulovacuolar degeneration., PMID:22968343
Endosomal sorting related protein CHMP2B is localized in Lewy bodies and glial cytoplasmic inclusions in α-synucleinopathy., PMID:22947304
Immunopositivity for ESCRT-III subunit CHMP2B in granulovacuolar degeneration of neurons in the Alzheimer's disease hippocampus., PMID:20420883
Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations., PMID:20223751
Distinct genetic forms of frontotemporal dementia., PMID:18703462
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)., PMID:16807408
For research use only. Not for human or drug use.
