Catalog No.
RHK31002
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO, m6A(m)-demethylase FTO, mRNA N(6)-methyladenosine demethylase FTO, KIAA1752, tRNA N1-methyl adenine demethylase FTO, U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO, Fat mass and obesity-associated protein, FTO, mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO, Alpha-ketoglutarate-dependent dioxygenase FTO
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9C0B1
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2L75
Lactylation of HDAC1 Confers Resistance to Ferroptosis in Colorectal Cancer., PMID:39888307
Tumor-derived CCL15 regulates RNA m6A methylation in cancer-associated fibroblasts to promote hepatocellular carcinoma growth., PMID:39734010
Biofunctional photoelectrochemical/electrochemical immunosensor based on BiVO4/BiOI-MWCNTs and Au@PdPt for alpha-fetoprotein detection., PMID:38972159
Targeting the oncogenic m6A demethylase FTO suppresses tumourigenesis and potentiates immune response in hepatocellular carcinoma., PMID:38839271
Fabrication of a Label-Free Immunosensor Using Surface-Engineered AuPt@GQD Core-Shell Nanocomposite for the Selective Detection of Trace Levels of Escherichia coli from Contaminated Food Samples., PMID:38816970
Gold nanostructure-enhanced immunosensing: ultra-sensitive detection of VEGF tumor marker for early disease diagnosis., PMID:38714678
Correction: Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/ GPX4 expression., PMID:38693552
A Four-Week High-Fat Diet Induces Anxiolytic-like Behaviors through Mature BDNF in the mPFC of Mice., PMID:38672038
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression., PMID:38600610
The Molecular Basis of Human ALKBH3 Mediated RNA N1 -methyladenosine (m1 A) Demethylation., PMID:38158383
Lung Cancer Cell-Derived Exosome Detection Using Electrochemical Approach towards Early Cancer Screening., PMID:38139054
Membraneless, self-powered immunosensing of a cardiac biomarker by exploiting a PEC platform based on CaBi2Ta2O9 combined with bismuth oxyiodides., PMID:37990986
A digital multimeter-based portable photoelectrochemical immunoassay for the detection of cardiac troponin I with enzymatic biocatalytic precipitation., PMID:37248854
Photoelectrochemical immunoassay of squamous cell carcinoma antigen based on CuO/nitrogen-doped porous carbon-ZnO biolabeling and a type-II In2O3/AgBiS2 heterojunction., PMID:37099090
Non-fouling polymer brush grafted fluorine-doped tin oxide enabled optical and chemical enhancement for sensitive label-free antibody microarrays., PMID:37097479
Photoelectrochemical Determination of Cardiac Troponin I as a Biomarker of Myocardial Infarction Using a Bi2S3 Film Electrodeposited on a BiVO4-Coated Fluorine-Doped Tin Oxide Electrode., PMID:36979591
MC-Au/MSS-Z8 porous network assisted advanced electrochemical immunosensing of 25-hydroxyvitamin D3., PMID:36821967
Chitosan/genipin modified electrode for voltammetric determination of interleukin-6 as a biomarker of sepsis., PMID:36441080
m6A methylation regulators as predictors for treatment of advanced urothelial carcinoma with anti-PDL1 agent., PMID:36189296
Label-Free Immunosensor Based on Polyaniline-Loaded MXene and Gold-Decorated β-Cyclodextrin for Efficient Detection of Carcinoembryonic Antigen., PMID:36005052
Photoelectrochemical immunosensor for the sensitive detection of neuron-specific enolase based on the effect of Z-scheme WO3/NiCo2O4 nanoarrays p-n heterojunction., PMID:35679647
Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1., PMID:35647519
Label free detection of SARS CoV-2 Receptor Binding Domain (RBD) protein by fabrication of gold nanorods deposited on electrochemical immunosensor (GDEI)., PMID:35635976
Photoelectrochemical sandwich immunoassay of CYFRA21-1 based on In2O3/WO3 type-II heterojunction and CdS quantum dots-polydopamine nanospheres labeling., PMID:35611759
Association Among the Gut Microbiome, the Serum Metabolomic Profile and RNA m6A Methylation in Sepsis-Associated Encephalopathy., PMID:35432460
Electrochemical Detection of Alzheimer's Disease Biomarker, β-Secretase Enzyme (BACE1), With One-Step Synthesized Reduced Graphene Oxide., PMID:35402415
Fat mass and obesity-associated protein regulates arecoline-exposed oral cancer immune response through programmed cell death-ligand 1., PMID:35289035
A lethal model of Leptospira infection in hamster nasal mucosa., PMID:35192629
Dual-template rectangular nanotube molecularly imprinted polypyrrole for label-free impedimetric sensing of AFP and CEA as lung cancer biomarkers., PMID:34942484
Electrochemical immunosensor for detection of avian Salmonellosis based on electroactive reduced graphene oxide (rGO) modified electrode., PMID:34906818
Electroactive reduced graphene oxide for highly sensitive detection of secretory non-structural 1 protein: A potential diagnostic biomarker for Japanese encephalitis virus., PMID:34864242
Label-free detection of SARS-CoV-2 Spike S1 antigen triggered by electroactive gold nanoparticles on antibody coated fluorine-doped tin oxide (FTO) electrode., PMID:34794571
Chemiluminescence-Derived Self-Powered Photoelectrochemical Immunoassay for Detecting a Low-Abundance Disease-Related Protein., PMID:34554727
m6A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2., PMID:34536357
RNA Demethylase FTO Mediated RNA m6A Modification Is Involved in Maintaining Maternal-Fetal Interface in Spontaneous Abortion., PMID:34350169
Integrated analysis of m6A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension., PMID:34310344
End-labeling-based electrochemical strategy for detection of adenine methylation in nucleic acid by differential pulse voltammetry., PMID:34254196
The m6A landscape of polyadenylated nuclear (PAN) RNA and its related methylome in the context of KSHV replication., PMID:34187903
Regulatory Mechanisms of the RNA Modification m6A and Significance in Brain Function in Health and Disease., PMID:34093133
Irx3 and Irx5 in Ins2-Cre+ cells regulate hypothalamic postnatal neurogenesis and leptin response., PMID:33859429
A passive direct methanol fuel cell as transducer of an electrochemical sensor, applied to the detection of carcinoembryonic antigen., PMID:33309216
Ultrasensitive detection of interleukin 1α using 3-phosphonopropionic acid modified FTO surface as an effective platform for disposable biosensor fabrication., PMID:33254051
A label-free photoelectrochemical immunosensor for carcinoembryonic antigen detection based on a g-C3N4/CdSe nanocomposite., PMID:33107868
A novel near-infrared light-responsive photoelectrochemical platform for detecting microcystin-LR in fish based on Ag2S cubes and plasmonic Au nanoparticles., PMID:33076071
Decreased Peripheral Blood ALKBH5 Correlates with Markers of Autoimmune Response in Systemic Lupus Erythematosus., PMID:32685056
Antibody-free enzyme-assisted chemical approach for detection of N6-methyladenosine., PMID:32341502
Epitranscriptomics in liver disease: Basic concepts and therapeutic potential., PMID:32330603
An Electrochemical Immunosensor Based on a Self-Assembled Monolayer Modified Electrode for Label-Free Detection of α-Synuclein., PMID:31979160
Photoelectrochemical immunosensor based on CdSe@BiVO4 Co-sensitized TiO2 for carcinoembryonic antigen., PMID:31929086
Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes., PMID:31822664
For research use only. Not for human or drug use.
