Catalog No.
YHC97401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu29-Gln366
Predicted molecular weight
39.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13473
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LGP-96, CD107b, LAMP2, CD107 antigen-like family member B, Lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2, LAMP-2
Cell-specific protein expression in Alzheimer's disease prefrontal cortex., PMID:40465637
Proteomic analysis of human follicular fluid based on the 4D label free method to identify proteins that may affect oocyte quality in hyperandrogenic PCOS patients., PMID:40444232
Downhill running induced mitophagy in rat soleus muscle via the AMPK pathway., PMID:40411707
Click-constructed modular signal aptamer chimeras enable receptor-independent degradation of membrane proteins., PMID:40388621
GPX4 degradation contributes to heat stress-induced liver injury via chaperone-mediated autophagy., PMID:40368268
Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress., PMID:40360527
Deficiency of HSF4 Increases the Secretion of Small Extracellular Vesicles via Upregulation of Chaperone-Mediated Autophagy., PMID:40211689
Overlapping functions between Lamp2a and Lamp2b in cardiac autophagy., PMID:40202173
TFEB and TFE3 regulate STING1-dependent immune responses by controlling type I interferon signaling., PMID:40195022
Mechanism of Tau protein incorporation into exosomes via cooperative recognition of KFERQ-like motifs by LAMP2A and HSP70., PMID:40187566
LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia., PMID:40178973
Atomistic Insights into gp82 Binding: A Microsecond, Million-Atom Exploration of Trypanosoma cruzi Host-Cell Invasion., PMID:40152296
Enhanced therapeutic efficacy of anti-PD-1 blockade by targeting LAMP2A inhibits lysosomal degradation of STING and TBK1., PMID:40083918
Function of lamp2 Gene Response to Vibrio vulnificus Infection and LPS Stimulation in the Half-Smooth Tongue Sole (Cynoglossus semilaevis)., PMID:40076623
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518
Chaperone-mediated autophagy regulates the metastatic state of mesenchymal tumors., PMID:40055574
TFE3 fusion proteins promote the progression of TFE3 rearranged renal cell carcinoma via enhancing chaperone-mediated lipophagy., PMID:40050998
[miR-207 targets autophagy-associated protein LAMP2 to regulate the mechanism of macrophage-mycobacterium tuberculosis interaction]., PMID:40047468
The lysosomal-associated membrane protein 2-macroautophagy pathway is involved in the regulatory effects of hippocampal aromatase on Aβ accumulation and AD-like behavior., PMID:39983826
Mycobacterium bovis Mb3523c protein regulates host ferroptosis via chaperone-mediated autophagy., PMID:39968901
PHLPP and LAMP2 predict favorable treatment response and survival in multiple myeloma patients who receive induction treatment with bortezomib., PMID:39951232
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis., PMID:39924645
VPS41 recruits biosynthetic LAMP-positive vesicles through interaction with Arl8b., PMID:39907656
Lamp2 Deficiency Enhances Susceptibility to Oxidative Stress-Induced RPE Degeneration., PMID:39898910
Limiting cap-dependent translation increases 20S proteasomal degradation and protects the proteomic integrity in autophagy-deficient skeletal muscle., PMID:39878121
VEXAS, Chediak-Higashi syndrome and Danon disease: myeloid cell endo-lysosomal pathway dysfunction as a common denominator?, PMID:39865233
Hypoxia-triggered ERRα acetylation enhanced its oncogenic role and promoted progression of renal cell carcinoma by coordinating autophagosome-lysosome fusion., PMID:39820331
Dopamine degrades ferritin by chaperone-mediated autophagy to elevate mitochondrial iron level in astroglial cells., PMID:39818240
Insufficient MIRO1 contributes to declined oocyte quality during reproductive aging., PMID:39815032
Tracking Chaperone-Mediated Autophagy Flux with a pH-Resistant Fluorescent Reporter., PMID:39795875
Nonreceptor tyrosine kinase ABL1 regulates lysosomal acidification by phosphorylating the ATP6V1B2 subunit of the vacuolar-type H+-ATPase., PMID:39757940
CircRNA CDR1AS promotes cardiac ischemia-reperfusion injury in mice by triggering cardiomyocyte autosis., PMID:39755856
The effect of molecular chaperone mediated autophagy on ApoE expression in retinal pigment epithelial cells: Molecular structure and protein action mechanism., PMID:39719232
Effects of orally exposed SiO2 nanoparticles on lipid profiles in gut-liver axis of mice., PMID:39708451
[Exploring effects and mechanisms of Agrimoniae Herba-Coptidis Rhizoma containing serum on colorectal cancer cells via LAMP2A-mediated autophagy]., PMID:39701784
Lysosomal damage due to cholesterol accumulation triggers immunogenic cell death., PMID:39663580
Quercetin inhibits hydrogen peroxide-induced cleavage of heat shock protein 90 to prevent glutathione peroxidase 4 degradation via chaperone-mediated autophagy., PMID:39647465
Autophagy markers expression pattern in developing liver of the yotari (dab1-/-) mice and humans., PMID:39647211
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria., PMID:39643606
Apigenin Reduces Lipid Droplet Accumulation in Hepatocytes by Enhancing Chaperone-Mediated Autophagy via AMPK., PMID:39632069
The essential role of TTC28 in maintaining chromosomal stability via HSPA8 chaperone-mediated autophagy., PMID:39630868
Impaired chaperone-mediated autophagy leads to abnormal SORT1 (sortilin 1) turnover and CES1-dependent triglyceride hydrolysis., PMID:39611307
Chaperone-Mediated Autophagy Alleviates Cerebral Ischemia-Reperfusion Injury by Inhibiting P53-Mediated Mitochondria-Associated Apoptosis., PMID:39576398
Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease., PMID:39556016
Chaperone-mediated autophagy (CMA) confers neuroprotection of HBO preconditioning against stroke., PMID:39522743
Selective protein degradation through chaperone‑mediated autophagy: Implications for cellular homeostasis and disease (Review)., PMID:39513615
The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR-99a/mTOR-Mediated Autophagy and Apoptosis., PMID:39513392
Heterogeneity of late endosome/lysosomes shown by multiplexed DNA-PAINT imaging., PMID:39485275
History and Perspective of LAMP-2 Deficiency (Danon Disease)., PMID:39456205
Reconstitution of Rab11-FIP4 Expression Rescues Cellular Homeostasis in Cystinosis., PMID:39434668
For research use only. Not for human or drug use.
