Catalog No.
RHJ85101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, WB: 1:1000-1:2000
Target
49 kDa TBP-interacting protein, Nuclear matrix protein 238, NMP 238, TAP54-alpha, RuvB-like 1, INO80H, 54 kDa erythrocyte cytosolic protein, TIP60-associated protein 54-alpha, 49 kDa TATA box-binding protein-interacting protein, RUVBL1, Pontin 52, TIP49, INO80 complex subunit H, ECP-54, TIP49A, NMP238, TIP49a
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y265
Applications
FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2L04
Detection of Anti-RuvBL1/2 Autoantibodies by Targeted Liquid Chromatography-Tandem Mass Spectrometry., PMID:40498123
Identification of biomarkers of shrinkage modes after neoadjuvant therapy in HER-2 positive breast cancer., PMID:40143733
Anti-RuvBL1/2 Autoantibodies Detection in a Patient with Overlap Systemic Sclerosis and Polymyositis., PMID:36810518
Identification of new telomere- and telomerase-associated autoantigens in systemic sclerosis., PMID:36634459
Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers., PMID:35716254
Anti-RuvBL1/2 autoantibodies in patients with systemic sclerosis or idiopathic inflammatory myopathy and a nuclear speckled pattern., PMID:35027396
Molecular Basis of Accelerated Aging with Immune Dysfunction-Mediated Inflammation (Inflamm-Aging) in Patients with Systemic Sclerosis., PMID:34943909
Leishmania major RUVBL1 has a hexameric conformation in solution and, in the presence of RUVBL2, forms a heterodimer with ATPase activity., PMID:33775623
Pathogenic roles of autoantibodies in systemic sclerosis: Current understandings in pathogenesis., PMID:35382028
A case of anti-RuvBL1/2 antibody-positive systemic sclerosis overlapping with myositis., PMID:32031537
Prevalence of auto-antibodies associated to pulmonary arterial hypertension in scleroderma - A review., PMID:30316987
Anti-nuclear autoantibodies in systemic sclerosis : News and perspectives., PMID:35382013
The clinico-serological spectrum of overlap myositis., PMID:30074509
Presence of anti-eukaryotic initiation factor-2B, anti-RuvBL1/2 and anti-synthetase antibodies in patients with anti-nuclear antibody negative systemic sclerosis., PMID:29294089
What is the third serological marker associated with immune-mediated necrotizing myopathy?, PMID:28067601
Case of anti-RuvBL1/2 antibody-positive morphea and polymyositis., PMID:27786369
Methylation analysis of histone H4K12ac-associated promoters in sperm of healthy donors and subfertile patients., PMID:25806092
An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex., PMID:25312759
A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women., PMID:24957886
Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement., PMID:24023044
Translatome analysis of CHO cells to identify key growth genes., PMID:23876478
Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers., PMID:22886747
Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype., PMID:21781345
Nuclear proteome analysis of monkey embryonic stem cells during differentiation., PMID:20091144
Reptin52 expression during in vitro neural differentiation of human embryonic stem cells., PMID:19444951
Pontin is localized in nucleolar fibrillar centers., PMID:18548265
Increased pontin expression in human colorectal cancer tissue., PMID:17442372
The ATP-dependent helicase RUVBL1/TIP49a associates with tubulin during mitosis., PMID:14506706
Purification, cloning, and characterization of a profibrinolytic plasminogen-binding protein, TIP49a., PMID:11027681
Molecular shape and ATP binding activity of rat p50, a putative mammalian homologue of RuvB DNA helicase., PMID:10050036
TIP49, homologous to the bacterial DNA helicase RuvB, acts as an autoantigen in human., PMID:9588198
For research use only. Not for human or drug use.
