Catalog No.
YHC96401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala23-Lys169
Predicted molecular weight
19.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13073
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytochrome c oxidase polypeptide IV, COX4, COX4I1, COX IV-1, Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase subunit IV isoform 1
Long-Term Functional and Structural Renoprotection After Experimental Acute Kidney Injury in Subclinical Chronic Kidney Disease In Vivo., PMID:40429761
Convergent evolution in nuclear and mitochondrial OXPHOS subunits underlies the phylogenetic discordance in deep lineages of Squamata., PMID:40239883
BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammation., PMID:40195021
Inhibition of PINK1 senses ROS signaling to facilitate neuroblastoma cell pyroptosis., PMID:40160153
Salmonella Typhimurium persistently infects host via its effector SseJ-induced PHB2-mediated mitophagy., PMID:39902787
Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress., PMID:39526436
Exercise preconditioning mitigates Ischemia-Reperfusion injury in rats by enhancing mitochondrial respiration., PMID:39461659
Melatonin protects against sarcopenia in middle-aged mice., PMID:39385610
Berberine Attenuates Acetamiprid Exposure-Induced Mitochondrial Dysfunction and Apoptosis in Rats via Regulating the Antioxidant Defense System., PMID:39189176
Artificial targeting of autophagy components to mitochondria reveals both conventional and unconventional mitophagy pathways., PMID:39177530
Spautin-1 promotes PINK1-PRKN-dependent mitophagy and improves associative learning capability in an alzheimer disease animal model., PMID:39051473
Dietary resveratrol improves the flesh quality of Siberian sturgeon (Acipenser baerii) by enhancing myofiber growth, nutrient accumulation and antioxidant capacity., PMID:38789922
Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function., PMID:38718733
Proteomics Reveals the Obstruction of Cellular ATP Synthesis in the Ruminal Epithelium of Growth-Retarded Yaks., PMID:38672391
The role of uterus mitochondrial function in high-fat diet-related adverse pregnancy outcomes and protection by resveratrol., PMID:38573228
Tumor Necrosis Factor Receptor-2 Signals Clear-Cell Renal Carcinoma Proliferation via Phosphorylated 4E Binding Protein-1 and Mitochondrial Gene Translation., PMID:38537932
Cannabidiol protects C2C12 myotubes against cisplatin-induced atrophy by regulating oxidative stress., PMID:38406827
Equisetin inhibits adiposity through AMPK-dependent regulation of brown adipocyte differentiation., PMID:38327434
Improving the Aerobic Capacity in Fingerlings of European Sea Bass (Dicentrarchus labrax) through Moderate and Sustained Exercise: A Metabolic Approach., PMID:38254443
Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells., PMID:38252645
The protective effect of caffeine against oxalate-induced epithelial-mesenchymal transition in renal tubular cells via mitochondrial preservation., PMID:38198962
Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro through Nrf2/HO-1 and Akt/mTOR pathways., PMID:38006930
Cholesterol induction in CD8+ T cell exhaustion in colorectal cancer via the regulation of endoplasmic reticulum-mitochondria contact sites., PMID:37919522
MTFP1 is a mitophagy receptor that operates in PINK1/PRKN-dependent mitophagy and promotes oral cancer cell survival., PMID:40395309
Neuroprotective potential of berberine against acetamiprid induced toxicity in rats: Implication of oxidative stress, mitochondrial alterations, and structural changes in brain regions., PMID:37350525
E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism., PMID:37275915
Mitochondrial respiration analysis in permeabilized porcine left ventricular and human right atrial specimens with ischemia-reperfusion., PMID:37235522
The Role of G3BP1 Gene Mediates P38 MAPK/JNK Pathway in Testicular Spermatogenic Dysfunction Caused by Cyfluthrin., PMID:37235265
Acute valproate exposure affects proneural factor expression by increasing FOXO3 in the hippocampus of juvenile mice with a sex-based difference., PMID:37019270
Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCδ Activator., PMID:36982784
[Anti-depression targets and mechanism study of Kaixin San]., PMID:36725237
Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism., PMID:36674794
The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagy., PMID:36588386
Calcitriol potentially alters HeLa cell viability via inhibition of autophagy., PMID:36149174
Skeletal Muscle Mitochondrial and Perilipin Content in a Cohort of Obese Subjects Undergoing Moderate and High Intensity Training., PMID:36144258
Energy Substrate Transporters in High-Grade Ovarian Cancer: Gene Expression and Clinical Implications., PMID:36012230
Evidence of a role for cAMP in mitochondrial regulation in ovarian granulosa cells., PMID:35944223
The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins., PMID:35804909
Liver injury in Wilson's disease: An immunohistochemical study., PMID:35477108
Cytochrome c oxidase mediates labile iron level and radioresistance in glioblastoma., PMID:35476930
Replicative Stress Coincides with Impaired Nuclear DNA Damage Response in COX4-1 Deficiency., PMID:35456968
CircRNA608-microRNA222-PINK1 axis regulates the mitophagy of hepatic stellate cells in NASH related fibrosis., PMID:35436629
Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner., PMID:35415678
COX4-like, a Nuclear-Encoded Mitochondrial Gene Duplicate, Is Essential for Male Fertility in Drosophila melanogaster., PMID:35327978
Zn(II) 5,5-Diethylbarbiturate Complex Selectively Induces Apoptosis in Breast Cancer and Breast Cancer Stem-Like Cells., PMID:35254725
Butyrate Ameliorates Mitochondrial Respiratory Capacity of The Motor-Neuron-like Cell Line NSC34-G93A, a Cellular Model for ALS., PMID:35204833
Propionate alleviates fatty acid-induced mitochondrial dysfunction, oxidative stress, and apoptosis by upregulating PPARG coactivator 1 alpha in hepatocytes., PMID:35181129
Seasonal changes in mitochondrial bioenergetics and physiological performance of the bluegill sunfish, Lepomis macrochirus, from a shallow, Midwest river., PMID:35180965
Autophagy modulation in resveratrol protective effects on steroidogenesis in high-fat diet-fed mice and H2O2-challenged TM3 cells., PMID:35000049
Acute Valproate Exposure Induces Mitochondrial Biogenesis and Autophagy with FOXO3a Modulation in SH-SY5Y Cells., PMID:34685502
For research use only. Not for human or drug use.
