Catalog No.
RHJ79501
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
VAV3, Guanine nucleotide exchange factor VAV3, VAV-3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UKW4
Applications
FCM, IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2K84
Rs7537605 polymorphism in VAV3 gene and rs28665122 polymorphism in SEPS gene are not associated with Hashimoto's thyroiditis in North-East Algerian population., PMID:37092056
Identification of key genes involved in tumor immune cell infiltration and cetuximab resistance in colorectal cancer., PMID:33632198
Vav family proteins constitute disparate branching points for distinct BCR signaling pathways., PMID:32671844
Profiling the origin, dynamics, and function of traction force in B cell activation., PMID:30087179
A Novel Vav3 Homolog Identified in Lamprey, Lampetra japonica, with Roles in Lipopolysaccharide-Mediated Immune Response., PMID:28937614
The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton., PMID:27816490
Transcriptomic changes associated with DKK4 overexpression in pancreatic cancer cells detected by RNA-Seq., PMID:26880586
Immunohistochemical analysis of the natural killer cell cytotoxicity pathway in human abdominal aortic aneurysms., PMID:25993291
A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans., PMID:24722205
Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state., PMID:21427288
Vav3 is involved in GABAergic axon guidance events important for the proper function of brainstem neurons controlling cardiovascular, respiratory, and renal parameters., PMID:20926682
Proteomic characterization of the cellular response to chemopreventive triterpenoid astragaloside IV in human hepatocellular carcinoma cell line HepG2., PMID:20126993
B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin., PMID:19586920
Osteopetrosis with micro-lacunar resorption because of defective integrin organization., PMID:19546854
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2., PMID:16174766
Murine gamma-herpesvirus 68 latency protein M2 binds to Vav signaling proteins and inhibits B-cell receptor-induced cell cycle arrest and apoptosis in WEHI-231 B cells., PMID:16150693
Vav proteins regulate peripheral B-cell survival., PMID:15941910
Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK., PMID:12818159
Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line., PMID:12234921
Vav3 is regulated during the cell cycle and effects cell division., PMID:11917103
Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation., PMID:11805146
Vav family proteins couple to diverse cell surface receptors., PMID:10938113
Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav., PMID:10669745
For research use only. Not for human or drug use.
