Catalog No.
RHJ56501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
VDUP1, Vitamin D3 up-regulated protein 1, TXNIP, Thioredoxin-binding protein 2, Thioredoxin-interacting protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H3M7
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2K19
M2 macrophage derived exosomal miR-20a-5p ameliorates trophoblast pyroptosis and placental injuries in obstetric antiphospholipid syndrome via the TXNIP/NLRP3 axis., PMID:40127859
Cordycepin mediates pyroptosis in HCC through the upregulation of TXNIP and synergizes with anti-PD-L1 immunotherapy., PMID:40008893
A novel application perspective of the clinical-used drug verapamil on osteoporosis via targeting Txnip., PMID:39876975
1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol treatment inhibits abnormal tumor growth by regulating neutrophil infiltration in a non-small cell lung carcinoma mouse model., PMID:39137654
Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane., PMID:36979492
A bifunctional fusion protein protected against diabetic nephropathy by suppressing NLRP3 activation., PMID:36843198
The anti-inflammatory feature of glucagon-like peptide-1 and its based diabetes drugs-Therapeutic potential exploration in lung injury., PMID:36386481
Panax notoginseng saponin R1 attenuates allergic rhinitis through AMPK/Drp1 mediated mitochondrial fission., PMID:35623408
Localization of Thioredoxin-Interacting Protein in Aging and Alzheimer's Disease Brains., PMID:39483368
The Protective Role of Cirsilineol against Ovalbumin-Induced Allergic Rhinitis in Mice by Suppression of Inflammation and Oxidative Stress., PMID:34587405
Titanium Dioxide Nanoparticles Exacerbate Allergic Airway Inflammation via TXNIP Upregulation in a Mouse Model of Asthma., PMID:34576095
Expression of recombinant classical swine fever virus E2 glycoprotein by endogenous Txnip promoter in stable transgenic CHO cells., PMID:32774204
Metformin Protects ARPE-19 Cells from Glyoxal-Induced Oxidative Stress., PMID:32695253
DRH1 - a novel blood-based HPV tumour marker., PMID:32535546
Connexin43 Is Required for the Effective Activation of Spleen Cells and Immunoglobulin Production., PMID:31752090
Dulaglutide inhibits high glucose- induced endothelial dysfunction and NLRP3 inflammasome activation., PMID:31302140
Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression., PMID:29475852
Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity., PMID:27929088
Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress., PMID:27554968
Melatonin rescues cardiac thioredoxin system during ischemia-reperfusion injury in acute hyperglycemic state by restoring Notch1/Hes1/Akt signaling in a membrane receptor-dependent manner., PMID:27753144
Thioredoxin-Interacting Protein (TXNIP) Suppresses Expression of Glutamine Synthetase by Inducing Oxidative Stress in Retinal Muller Glia Under Diabetic Conditions., PMID:27131835
SjCa8, a calcium-binding protein from Schistosoma japonicum, inhibits cell migration and suppresses nitric oxide release of RAW264.7 macrophages., PMID:26445908
Foam cell-derived 4-hydroxynonenal induces endothelial cell senescence in a TXNIP-dependent manner., PMID:25754218
E2F1 induces miR-224/452 expression to drive EMT through TXNIP downregulation., PMID:25341426
Transcription factor Ets1 regulates expression of thioredoxin-interacting protein and inhibits insulin secretion in pancreatic β-cells., PMID:24897113
Functional study of a genetic marker allele associated with resistance to Ascaris suum in pigs., PMID:24709292
Nitrosative/oxidative stress conditions regulate thioredoxin-interacting protein (TXNIP) expression and thioredoxin-1 (TRX-1) nuclear localization., PMID:24376827
Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo., PMID:24342772
PDT-induced epigenetic changes in the mouse cerebral cortex: a protein microarray study., PMID:24055374
Anti-cytokine therapies in T1D: Concepts and strategies., PMID:23510726
Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis., PMID:23393387
TXNIP regulates germinal center generation by suppressing BCL-6 expression., PMID:20156484
Overexpression of thioredoxins 1 and 2 increases retinal ganglion cell survival after pharmacologically induced oxidative stress, optic nerve transection, and in experimental glaucoma., PMID:20126492
Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses., PMID:18425727
Regulation of the bioavailability of thioredoxin in the lens by a specific thioredoxin-binding protein (TBP-2)., PMID:17603038
For research use only. Not for human or drug use.
