Catalog No.
RHJ35302
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
IRF-7, IRF7, Interferon regulatory factor 7
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92985
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2J58
IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints., PMID:40439584
Type I interferon drives T cell cytotoxicity by upregulation of interferon regulatory factor 7 in autoimmune kidney diseases in mice., PMID:40393992
Yellow fever virus infection alters mitochondrial network dynamics and trigger IFN-I response via TLR2 pathway., PMID:40300356
Characterisation of a Japanese Encephalitis virus genotype 4 isolate from the 2022 Australian outbreak., PMID:40295675
Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling., PMID:40260261
Chemotherapy-Mediated Induction of PD-L1 via SEI1 Facilitates Myeloma Immune Evasion., PMID:40135791
IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints., PMID:39974943
Tim-3 promotes viral infection by suppressing the USP25-TRAF3-IRF7 signaling pathway., PMID:39946759
Inhibiting Tyrosine Kinase 2 Ameliorates Antiphospholipid Syndrome Nephropathy., PMID:39742289
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267
Isolation and identification of hybrid snakehead rhabdovirus (HSHRV) and its immune response in the hybrid Snakehead((male Channa argus × female Channa maculata)., PMID:39332542
Deficiency of Tlr7 and Irf7 in mice increases the severity of COVID-19 through the reduced interferon production., PMID:39289468
Microglia either promote or restrain TRAIL-mediated excitotoxicity caused by Aβ1-42 oligomers., PMID:39218898
Phage Immunoprecipitation-Sequencing Reveals CDHR5 Autoantibodies in Select Patients With Interstitial Lung Disease., PMID:38952015
Profiling of Early Immune Responses to Vaccination Using THP-1-Derived Dendritic Cells., PMID:38791547
Impact of the host immune response on the development of equine herpesvirus myeloencephalopathy in horses., PMID:38767608
Melanoma Derived Exosomes Amplify Radiotherapy Induced Abscopal Effect via IRF7/I-IFN Axis in Macrophages., PMID:38286661
Human inborn errors of immunity associated with IRF4., PMID:37809068
Interferon regulatory factor 7 modulates virus clearance and immune responses to alphavirus encephalomyelitis., PMID:37772825
Type I IFN Derived from Ly6Chi Monocytes Suppresses Type 2 Inflammation in a Murine Model of Atopic Dermatitis., PMID:37739337
Astrocytes evoke a robust IRF7-independent type I interferon response upon neurotropic viral infection., PMID:37737190
Sustained induction of IP-10 by MRP8/14 via the IFNβ-IRF7 axis in macrophages exaggerates lung injury in endotoxemic mice., PMID:37701855
TRIM5 Promotes Systemic Lupus Erythematosus Through CD4(+) T Cells and Macrophage., PMID:37614552
IRF7 and IFIT2 in mediating different hemorrhage outcomes for non-small cell lung cancer after bevacizumab treatment., PMID:37197507
Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies., PMID:36878637
Coxsackievirus A6 Infection Causes Neurogenic Pathogenesis in a Neonatal Murine Model., PMID:36851724
CD36 neutralisation blunts TLR2-IRF7 but not IRF3 pathway in neonatal mouse brain and immature human microglia following innate immune challenge., PMID:36759676
Aberrant B-Cell Activation in Systemic Lupus Erythematosus., PMID:36590680
Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination., PMID:36342455
Chilblains observed during the COVID-19 pandemic cannot be distinguished from classic, cold-related chilblains., PMID:36065533
BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein., PMID:35967447
A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients., PMID:35842705
Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion., PMID:35810186
Oral S2-Ag85 DNA Vaccine Activated Intestinal Cell dsDNA and RNA Sensors to Promote the Presentation of Intestinal Antigen., PMID:35465352
Two Conserved Phenylalanine Residues in the E1 Fusion Loop of Alphaviruses Are Essential for Viral Infectivity., PMID:35416719
Generation and functional analysis of single chain variable fragments (scFvs) targeting the nucleocapsid protein of Porcine epidemic diarrhea virus., PMID:35024918
Analysis of immune response induction mechanisms implicating the dose-sparing effect of transcutaneous immunization using a self-dissolving microneedle patch., PMID:34998604
Disulfiram Improves the Anti-PD-1 Therapy Efficacy by Regulating PD-L1 Expression via Epigenetically Reactivation of IRF7 in Triple Negative Breast Cancer., PMID:34858816
T cell and memory B cell responses in tetravalent DNA, tetravalent inactivated and tetravalent live-attenuated prime-boost dengue vaccines in rhesus macaques., PMID:34823910
The role of interferon regulatory factor 7 in the pathogenicity and immunogenicity of rabies virus in a mouse model., PMID:34661517
Proteome Modulation in Peripheral Blood Mononuclear Cells of Peste des Petits Ruminants Vaccinated Goats and Sheep., PMID:34631844
Amniotic membrane conditioned medium (AMCM) reduces inflammatory response on human limbal myofibroblast, and the potential role of lumican., PMID:34447239
The proliferation of belatacept-resistant T cells requires early IFNα pathway activation., PMID:34431219
An Experimental Model of Neuromyelitis Optica Spectrum Disorder-Optic Neuritis: Insights Into Disease Mechanisms., PMID:34367056
Molecular determinants of disease severity in urinary tract infection., PMID:34131331
Neutralizing interferon-α blocks inflammation-mediated vascular injury via PI3K and AMPK in systemic lupus erythematosus., PMID:34077562
LAMP-5 is an essential inflammatory-signaling regulator and novel immunotherapy target for mixed lineage leukemia-rearranged acute leukemia., PMID:33910331
Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer., PMID:33762320
Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A., PMID:33445752
Role of Host Immune and Inflammatory Responses in COVID-19 Cases with Underlying Primary Immunodeficiency: A Review., PMID:33337932
For research use only. Not for human or drug use.
