Catalog No.
RHJ34401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
ATP-binding cassette sub-family C member 2, Multidrug resistance-associated protein 2, Canalicular multispecific organic anion transporter 1, ABCC2, CMOAT, Canalicular multidrug resistance protein, MRP2, CMRP, CMOAT1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92887
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2J56
Functional expression of Bacillus thuringiensis Cry proteins on the surface of Bacillus subtilis spores., PMID:39877884
In vitro models to evaluate multidrug resistance in cancer cells: Biochemical and morphological techniques and pharmacological strategies., PMID:39363148
RNAi-based knockdown of candidate gut receptor genes altered the susceptibility of Spodoptera frugiperda and S. litura larvae to a chimeric toxin Cry1AcF., PMID:36710863
Anti-drug resistance, anti-inflammation, and anti-proliferation activities mediated by melatonin in doxorubicin-resistant hepatocellular carcinoma: in vitro investigations., PMID:36651944
Identification of single domain antibodies with insect cytotoxicity using phage-display antibody library screening and Plutella xylostella ATP-binding cassette transporter subfamily C member 2 (ABCC2) -based insect cell expression system., PMID:35346681
ABCC2 expression in papillary renal cell carcinoma provides better prognostic stratification than WHO/ISUP nucleolar grade., PMID:34958810
Interrupting tumor necrosis factor-alpha signaling prevents parenteral nutrition-associated cholestasis in mice., PMID:34664730
The Role of Specific ATP-Binding Cassette Transporters in the Acquired Resistance to Pyrrolobenzodiazepine Dimer-Containing Antibody-Drug Conjugates., PMID:32669316
Effect of GenX on P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 at the Blood-Brain Barrier., PMID:32212926
Isolation of a novel glycyrrhizin metabolite as a causal candidate compound for pseudoaldosteronism., PMID:30348944
Pharmacokinetics and pharmacogenomics of mycophenolic acid and its clinical correlations in maintenance immunosuppression for lupus nephritis., PMID:30215770
Immunohistochemical Assessment of the Expression of Biliary Transportation Proteins MRP2 and MRP3 in Hepatocellular Carcinoma and in Cholangiocarcinoma., PMID:29464551
Mechanism of inhibition of taurolithocholate-induced retrieval of plasma membrane MRP2 by cyclic AMP and tauroursodeoxycholate., PMID:29192063
DS-8201a, a new HER2-targeting antibody-drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2-positive gastric cancer T-DM1 resistance., PMID:28677116
Don't trust an(t)ybody - Pitfalls during investigation of candidate proteins for methylmercury transport at the placental interface., PMID:27324094
Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-60 trial of patients with aggressive CD20(+) B-cell lymphoma., PMID:25823784
Resistance and intolerance to statins., PMID:24996502
WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells., PMID:24903205
Expression of the ABC transport proteins MDR1 (ABCB1) and BCRP (ABCG2) in bovine rumen., PMID:24747985
A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO)., PMID:23953030
Effects of rhinacanthin-C on function and expression of drug efflux transporters in Caco-2 cells., PMID:23742857
ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds., PMID:23041646
Rat Mrp2 gene expression is regulated by an interleukin-1β-stimulated biphasic response with enhanced transcription and subcellular shuttling of YB-1., PMID:22361279
Novel roles of galectin-1 in hepatocellular carcinoma cell adhesion, polarization, and in vivo tumor growth., PMID:21391228
Quantitative immunofluorescent blotting of the multidrug resistance-associated protein 2 (MRP2)., PMID:21277982
Decreased hepatic breast cancer resistance protein expression and function in multidrug resistance-associated protein 2-deficient (TR⁻) rats., PMID:21106720
Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat., PMID:20719938
Presence of ecotoxicologically relevant Pgp and MRP transcripts and proteins in Cyprinid fish., PMID:20587391
High-activity p-glycoprotein, multidrug resistance protein 2, and breast cancer resistance protein membrane vesicles prepared from transiently transfected human embryonic kidney 293-epstein-barr virus nuclear antigen cells., PMID:20071452
[Effect of Lewis y antigen on regulating gene expression of partial drug resistance associated proteins in human ovarian cancer cell line RMG-I-H]., PMID:19771739
Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells., PMID:19771531
Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression., PMID:19603017
Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer., PMID:19020751
Detection of ABCC2, CYP2B6 and CYP3A4 in human peripheral blood mononuclear cells using flow cytometry., PMID:18929567
Absolute difference of hepatobiliary transporter multidrug resistance-associated protein (MRP2/Mrp2) in liver tissues and isolated hepatocytes from rat, dog, monkey, and human., PMID:18832477
Role of plasma proteins in pharmacokinetics of micafungin, an antifungal antibiotic, in analbuminemic rats., PMID:18591270
Expression and localization of ATP binding cassette (ABC) family of drug transporters in gastric hepatoid adenocarcinomas., PMID:18439156
Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes., PMID:18273864
Expression of the multidrug resistance proteins MRP2 and MRP3 in human cholangiocellular carcinomas., PMID:18226047
Expression, localization, and inducibility by bile acids of hepatobiliary transporters in the new polarized rat hepatic cell lines, Can 3-1 and Can 10., PMID:17909858
Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells., PMID:17825285
Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats., PMID:17437408
Phloracetophenone-induced choleresis in rats is mediated through Mrp2., PMID:17363469
Interaction between CD44 and hyaluronate induces chemoresistance in non-small cell lung cancer cell., PMID:17276588
Efflux of baicalin, a flavone glucuronide of Scutellariae Radix, on Caco-2 cells through multidrug resistance-associated protein 2., PMID:17227625
Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats., PMID:16504477
Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B., PMID:16109175
Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis., PMID:15841457
Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation., PMID:15821043
Directional trans-epithelial transport of organic anions in porcine LLC-PK1 cells that co-express human OATP1B1 (OATP-C) and MRP2., PMID:15652233
For research use only. Not for human or drug use.
