Catalog No.
RHJ31802
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Dedicator of cytokinesis protein 2, DOCK2, KIAA0209
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92608
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2J39
Multiple Immune Defects in Two Patients with Novel DOCK2 Mutations Result in Recurrent Multiple Infection Including Live Attenuated Virus Vaccine., PMID:36947335
SULT2B1-CS-DOCK2 axis regulates effector T-cell exhaustion in HCC microenvironment., PMID:36626623
First patient in the Iranian Registry with novel DOCK2 gene mutation, presenting with skeletal tuberculosis, and review of literature., PMID:34872585
Molecular mechanism of enhancing the immune effect of the Newcastle disease virus vaccine in broilers fed with Bacillus cereus PAS38., PMID:34647113
Investigating the Variation of TREC/KREC in Combined Immunodeficiencies., PMID:34418894
Dedicator of cytokinesis protein 2 couples with lymphoid enhancer-binding factor 1 to regulate expression of CD21 and B-cell differentiation., PMID:31405607
Wnt5a induces ROR1 to recruit DOCK2 to activate Rac1/2 in chronic lymphocytic leukemia., PMID:29678828
The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production., PMID:29503648
Growth of B Cell Receptor Microclusters Is Regulated by PIP2 and PIP3 Equilibrium and Dock2 Recruitment and Activation., PMID:29186690
Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency: DOCK8 and DOCK2., PMID:27890234
Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2., PMID:25076492
Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection., PMID:25031348
The Drosophila DOCK family protein sponge is involved in differentiation of R7 photoreceptor cells., PMID:23747680
Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses., PMID:22431588
Characterization of an mDock5-specific antibody and tissue-specific expression and subcellular localization of mDock5., PMID:19995334
An isoform of GTPase regulator DOCK4 localizes to the stereocilia in the inner ear and binds to harmonin (USH1C)., PMID:16464467
Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing., PMID:15357953
For research use only. Not for human or drug use.
