Catalog No.
RHJ23502
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
FRCP2, Fibronectin type III repeat-containing protein 2, Fibronectin type III domain-containing protein 5, FNDC5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8NAU1
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2J15
Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization., PMID:40415369
Irisin Improves Preeclampsia by Promoting Embryo Implantation and Vascular Remodeling., PMID:39540296
Exercise-induced interactions between skeletal muscle and bone via myokines and osteokine in mice: Role of FNDC5/irisin, IGF-1, and osteocalcin., PMID:39486601
Fibronectin type III domain-containing protein 5 (FNDC5)-like immunoreactivity and mRNA abundance in domestic animal tissues., PMID:38849027
MiR-143-3p/FNDC5 axis: a novel regulator of insulin sensitivity., PMID:37815745
Exercise hormone irisin prevents physical inactivity-induced cognitive decline in mice., PMID:35850397
Irisin-A Pancreatic Islet Hormone., PMID:35203466
HIF-1α Negatively Regulates Irisin Expression Which Involves in Muscle Atrophy Induced by Hypoxia., PMID:35055073
Serum irisin levels in patients with myasthenia gravis., PMID:34709479
Effects of GLP-1 receptor agonists on myokine levels and pro-inflammatory cytokines in patients with type 2 diabetes mellitus., PMID:34518091
Circulating Irisin Level and Thyroid Dysfunction: A Systematic Review and Meta-Analysis., PMID:33195690
Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo., PMID:32780016
Effect of single bout downhill running on the serum irisin concentrations in rats., PMID:32200682
Irisin: Still chasing shadows., PMID:32180552
Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor., PMID:31701659
Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia/Reperfusion., PMID:31191804
Serum irisin and apelin levels and markers of atherosclerosis in patients with subclinical hypothyroidism., PMID:30864627
Expression, purification and biological characterisation of recombinant human irisin (12.5 kDa)., PMID:30733760
Association between circulating irisin levels and epicardial fat in patients with treatment-naïve overt hyperthyroidism., PMID:29862847
Detection and quantitation of irisin in human cerebrospinal fluid by tandem mass spectrometry., PMID:29574076
5 years later: irisin detection still an issue., PMID:28710063
Factors associated with increased irisin levels in the type 1 diabetes mellitus., PMID:28222023
The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia., PMID:28183451
Irisin and Myostatin Levels in Patients with Graves' Disease., PMID:27986127
Irisin inhibition of growth hormone secretion in cultured tilapia pituitary cells., PMID:27693813
Irisin immunostaining characteristics of breast and ovarian cancer cells., PMID:27545213
Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes., PMID:27297797
Irisin immunohistochemistry in gastrointestinal system cancers., PMID:26963139
FNDC5 is produced in the stomach and associated to body composition., PMID:26961074
Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry., PMID:26278051
Circulating levels of irisin is elevated in hypothyroidism, a case-control study., PMID:26201007
Circulating irisin detection: Does it really work?, PMID:26008878
Biomedicine. Woes for 'exercise hormone'., PMID:25792309
Irisin - a myth rather than an exercise-inducible myokine., PMID:25749243
Does IRISIN Have a BRITE Future as a Therapeutic Agent in Humans?, PMID:24818073
Irisin is elevated in skeletal muscle and serum of mice immediately after acute exercise., PMID:24644429
Circulating irisin is associated with osteoporotic fractures in postmenopausal women with low bone mass but is not affected by either teriparatide or denosumab treatment for 3 months., PMID:24599275
Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?, PMID:24052909
Irisin-immunoreactivity in neural and non-neural cells of the rodent., PMID:23470775
For research use only. Not for human or drug use.
