Catalog No.
YHC93101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala37-Arg175
Predicted molecular weight
18.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12272
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Parathyroid hormone-like protein, PTHrP, PTH-rP, Parathyroid hormone-related protein, PTHrP[107-139], PLP, PTHRP, PTHLH
Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis., PMID:40501563
Genetic Comparison and Selection of Reproductive and Growth-Related Traits in Qinchuan Cattle and Two Belgian Cattle Breeds., PMID:40003088
Molecular Profiling of Odontoclasts during Physiological Tooth Replacement., PMID:39876039
Immunohistochemical expression of parathyroid hormone-related protein and ezrin in invasive breast carcinoma of no special type: a retrospective analysis., PMID:39827339
Proliferative behaviours of CD90-expressing chondrocytes under the control of the TSC1-mTOR/PTHrP-nuclear localisation segment pathway., PMID:39730094
The effects of different doses of compound enzyme preparations on the production performance, meat quality and rumen microorganisms of yak were studied by metagenomics and transcriptomics., PMID:39726957
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7., PMID:39352550
Regulation of Skeletal Development and Maintenance by Runx2 and Sp7., PMID:39337587
Mechanoinduction of PTHrP/cAMP-signaling governs proteoglycan production in mesenchymal stromal cell-derived neocartilage., PMID:39238313
Parathyroid Hormone Related Protein Mediated Hypercalcaemia Due to Metastatic Squamous Cell Carcinoma Originating from Pilonidal Disease: A Case Report., PMID:39212563
PTHrP participates in the bone destruction of middle ear cholesteatoma via promoting macrophage differentiation into osteoclasts induced by RANKL., PMID:39174879
Transcriptomic profiling of a late recurrent nuclear protein in testis carcinoma of the lung 14 years after the initial operation: a case report., PMID:39118893
A model-free and distribution-free multi-omics integration approach for detecting novel lung adenocarcinoma genes., PMID:39097651
[Single-cell transcriptomic sequencing coupled with Mendelian randomization analysis elucidates the pivotal role of CTSC in chronic rhinosinusitis]., PMID:38965845
Unveiling potential therapeutic targets for diabetes-induced frozen shoulder through Mendelian randomization analysis of the human plasma proteome., PMID:38719509
Weighted gene co-expression network analysis reveals key biomarkers and immune infiltration characteristics for bronchial epithelial cells from asthmatic patients., PMID:38640283
Spatiotemporal Evolution of Developing Palate in Mice., PMID:38619065
The spatio-temporal expression analysis of parathyroid hormone like hormone gene provides a new insight for bone growth of the antler tip tissue in sika deer., PMID:38419534
A novel heterozygous mutation in PTHLH causing autosomal dominant brachydactyly type E complicated with short stature., PMID:38407575
CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs., PMID:38375508
Skeletal growth is enhanced by a shared role for SOX8 and SOX9 in promoting reserve chondrocyte commitment to columnar proliferation., PMID:38346197
Single-cell analysis reveals ADGRL4+ renal tubule cells as a highly aggressive cell type in clear cell renal cell carcinoma., PMID:38287102
A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via Runx2., PMID:38058151
Differentially Expressed mRNA in Streptozotocin-Induced Diabetic Bladder Using RNA Sequencing Analysis., PMID:37798882
Identification of candidate genes and chemicals associated with osteoarthritis by transcriptome-wide association study and chemical-gene interaction analysis., PMID:37749624
Identification of a second genetic alteration in patients with SHOX deficiency individuals: a potential explanation for phenotype variability., PMID:37695807
Role of Parathyroid Hormone and Parathyroid Hormone-Related Protein in Protein-Energy Malnutrition., PMID:37664938
TMCO3, a Putative K+ :Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans., PMID:37554015
Parathyroid Hormone Related Protein (PTHrP)-Associated Molecular Signatures in Tissue Differentiation and Non-Tumoral Diseases., PMID:37508381
Regulation of Osteoblast to Osteocyte Differentiation by Cyclin-Dependent Kinase-1., PMID:37424388
A Network Pharmacology and Multi-Omics Combination Approach to Reveal the Effect of Strontium on Ca2+ Metabolism in Bovine Rumen Epithelial Cells., PMID:37298335
Isochromosome 12p Formation Regulates Vitamin D Metabolism in Testicular Cancer., PMID:37242266
Parathyroid Hormone (PTH)-Related Peptides Family: An Intriguing Role in the Central Nervous System., PMID:37240884
Network and pathway-based analysis of candidate genes associated with esophageal adenocarcinoma., PMID:36915458
Streptonigrin Mitigates Lung Cancer-induced Cachexia by Suppressing TCF4/TWIST1-induced PTHLH Expression., PMID:36854496
SLC17A9-PTHLH-EMT axis promotes proliferation and invasion of clear renal cell carcinoma., PMID:36590170
Identification and validation of novel biomarkers affecting bladder cancer immunotherapy via machine learning and its association with M2 macrophages., PMID:36439109
CEP55 3'-UTR promotes epithelial-mesenchymal transition and enhances tumorigenicity of bladder cancer cells by acting as a ceRNA regulating miR-497-5p., PMID:36374443
Characterization of somatic structural variations in 528 Chinese individuals with Esophageal squamous cell carcinoma., PMID:36272974
miR-200b-3p/ERG/PTHrP axis mediates the inhibitory effect of ethanol on the differentiation of fetal cartilage into articular cartilage., PMID:36174738
Parathyroid hormone-related protein (PTHrP)-dependent modulation of gene expression signatures in cancer cells., PMID:35953109
Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice., PMID:35950595
Is an association of acro-osteolysis, bone fragility, and enchondromatosis a newfound disease caused by an amplification of PTHLH? A case report., PMID:35908058
PGC1α Cooperates with FOXA1 to Regulate Epithelial Mesenchymal Transition through the TCF4-TWIST1., PMID:35897813
Parathyroid Hormone-Related Protein Inhibition Blocks Triple-Negative Breast Cancer Expansion in Bone Through Epithelial to Mesenchymal Transition Reversal., PMID:35720668
Whole Aspect of Runx2 Functions in Skeletal Development., PMID:35628587
RNA sequence analysis identified bone morphogenetic protein-2 (BMP2) as a biomarker underlying form deprivation myopia., PMID:35494490
Expression Profile of Myoepithelial Cells in DCIS: Do They Change From Protective Angels to Wicked Witches?, PMID:35467556
PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development., PMID:35440032
Polygonum cuspidatum Extract (Pc-Ex) Containing Emodin Suppresses Lung Cancer-Induced Cachexia by Suppressing TCF4/TWIST1 Complex-Induced PTHrP Expression., PMID:35406121