Catalog No.
RHH86801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
CREB-regulated transcription coactivator 2, TORC-2, Transducer of CREB protein 2, CRTC2, Transducer of regulated cAMP response element-binding protein 2, TORC2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q53ET0
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2H79
Effect of exercise and butyrate supplementation on microbiota composition and lipid metabolism., PMID:31454784
Transcription Factor STAT3 Serves as a Negative Regulator Controlling IgE Class Switching in Mice., PMID:31026806
Immunolocalisation of aromatase regulators liver kinase B1, phosphorylated AMP-activated protein kinase and cAMP response element-binding protein-regulated transcription co-activators in the human testis., PMID:26946412
CRTC2 activation in the suprachiasmatic nucleus, but not paraventricular nucleus, varies in a diurnal fashion and increases with nighttime light exposure., PMID:25080490
cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis., PMID:23595987
Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy., PMID:22407832
Regulation of mast cell survival and function by tuberous sclerosis complex 1., PMID:22362037
Isolation of the mTOR complexes by affinity purification., PMID:22125060
mTOR activity under hypoxia., PMID:22125059
Evaluation of the nutrient-sensing mTOR pathway., PMID:22125058
PI3K/mTOR signaling regulates prostatic branching morphogenesis., PMID:22015718
CREB coactivator CRTC2/TORC2 and its regulator calcineurin crucially mediate follicle-stimulating hormone and transforming growth factor β1 upregulation of steroidogenesis., PMID:21826657
AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling., PMID:20864035
Raptor is phosphorylated by cdc2 during mitosis., PMID:20169205
Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid., PMID:20027631
mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action., PMID:20022946
Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer., PMID:20010869
High-throughput screening for mTORC1/mTORC2 kinase inhibitors using a chemiluminescence-based ELISA assay., PMID:19895344
Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein., PMID:19299511
For research use only. Not for human or drug use.
