Catalog No.
RHH19901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
SRC1, RIP160, NCOA1, BHLHE74, Steroid receptor coactivator 1, Renal carcinoma antigen NY-REN-52, SRC-1, Nuclear receptor coactivator 1, NCoA-1, Protein Hin-2, Class E basic helix-loop-helix protein 74, bHLHe74
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15788
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2G63
NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis., PMID:38730334
Inhibition of steroid receptor coactivator-1 in the hippocampus impairs the consolidation and reconsolidation of contextual fear memory in mice., PMID:32006528
Improvement of sensitivity to tamoxifen in estrogen receptor-positive and Herceptin-resistant breast cancer cells., PMID:18768663
Functional conservation of the glutamine-rich domains of yeast Gal11 and human SRC-1 in the transactivation of glucocorticoid receptor Tau 1 in Saccharomyces cerevisiae., PMID:18070925
Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17., PMID:16497732
Complex agonist-like properties of ICI 182,780 (Faslodex) in human breast cancer cells that predominantly express progesterone receptor-B: implications for treatment resistance., PMID:16273221
Epitope analysis of PPARgamma monoclonal antibody Pgamma48.34A and its application for screening PPARgamma ligands., PMID:15680157
Expression and function of androgen receptor coactivators in prostate cancer., PMID:15663989
Inverse relationship between ER-beta and SRC-1 predicts outcome in endocrine-resistant breast cancer., PMID:15477868
Identification of a novel family of ankyrin repeats containing cofactors for p160 nuclear receptor coactivators., PMID:15184363
Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by beta-estradiol and 4-hydroxytamoxifen in human breast cancer., PMID:14715875
Expression of cAMP response element binding protein (CREB)-binding protein (CBP) and the implication in retinoic acid-inducible transcription activation in human salivary gland adenocarcinoma cell line HSG., PMID:14535629
Development of a versatile platform for nuclear receptor screening using AlphaScreen., PMID:12844440
Expression of sex steroid receptors and their co-factors in normal and malignant breast tissue: AIB1 is a carcinoma-specific co-activator., PMID:12725419
A homogeneous in vitro functional assay for estrogen receptors: coactivator recruitment., PMID:12554768
Role of the promyelocytic leukemia body in the dynamic interaction between the androgen receptor and steroid receptor coactivator-1 in living cells., PMID:12511612
An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1., PMID:12138096
Subcellular localization of the steroid receptor coactivators (SRCs) and MEF2 in muscle and rhabdomyosarcoma cells., PMID:11328858
Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1., PMID:10770489
A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo., PMID:10567404
Production and characterization of monoclonal antibodies to the steroid receptor coactivator AIB1., PMID:10475243
Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone., PMID:10196362
Distinct steady-state nuclear receptor coregulator complexes exist in vivo., PMID:9751728
Mapping the domains of the interaction of the vitamin D receptor and steroid receptor coactivator-1., PMID:9440810
p300 is a component of an estrogen receptor coactivator complex., PMID:8876171
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300., PMID:8855229