Catalog No.
RHG83401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:500-1:1000
Target
DSC4, Cadherin family member 3, DSC3, HT-CP, CDHF3, Desmocollin-3, Desmocollin-4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14574
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2F57
Prevalence and pathogenic activity of anti-desmocollin-3 antibodies in patients with pemphigus vulgaris and pemphigus foliaceus., PMID:39989391
Immunohistopathological analyses of a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3., PMID:39073162
Desmosomal Hyper-Adhesion Affects Direct Inhibition of Desmoglein Interactions in Pemphigus., PMID:38677661
Upregulation of Anti-Desmocollin 3 Antibodies in Pemphigus Diseases: A Case-control Study., PMID:38651843
Comparative Characterization of Human Meibomian Glands, Free Sebaceous Glands, and Hair-Associated Sebaceous Glands Based on Biomarkers, Analysis of Secretion Composition, and Gland Morphology., PMID:38542083
Pemphigus Autoantibodies to Desmocollin 3 but Not to Desmocollin 1 Directly Block Heterophilic Desmoglein/Desmocollin Transinteraction., PMID:38101510
A Novel In Vivo Active Pemphigus Model Targeting Desmoglein1 and Desmoglein3: A Tool Representing All Pemphigus Variants., PMID:37237515
Two cases of Hallopeau-type pemphigus vegetans with anti-desmoglein 1 and anti-desmocollin 3 antibodies without mucosal involvement., PMID:36305887
Gene expression profiling of laminin α3-blocked keratinocytes reveals an immune-independent mechanism of blistering., PMID:34796550
Human Desmocollin 3‒Specific IgG Antibodies Are Pathogenic in a Humanized HLA Class II Transgenic Mouse Model of Pemphigus., PMID:34265330
Autoantibodies to DSC3 in Pemphigus Exclusively Recognize Calcium-Dependent Epitope in Extracellular Domain 2., PMID:33766509
Atypical pemphigus with anti-desmocollin 2 and 3 antibodies, initially presenting as pemphigus vulgaris with anti-desmoglein 3 antibodies., PMID:32808594
Pemphigus Vulgaris and Foliaceus IgG Autoantibodies Directly Block Heterophilic Transinteraction between Desmoglein and Desmocollin., PMID:32142800
Paraneoplastic pemphigus associated with Waldenström's macroglobulinemia., PMID:32103535
The involvement of ADAM10 in acantholysis in mucocutaneous pemphigus vulgaris depends on the autoantibody profile of each patient., PMID:31370093
Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus., PMID:31275323
Detection of IgG Autoantibodies against Desmocollin-3 in Greek Patients with Pemphigus., PMID:31032784
Synergy among non-desmoglein antibodies contributes to the immunopathology of desmoglein antibody-negative pemphigus vulgaris., PMID:30692201
Nonclassical pemphigus with exclusively IgG anti-desmocollin 3-specific antibodies., PMID:30671942
Elevated serum eosinophil cationic protein and transforming growth factor-α levels in a patient with pemphigus vegetans., PMID:29862541
Pemphigus herpetiformis with autoantibodies to desmocollins 1, 2 and 3., PMID:29333762
Image Gallery: Juvenile autoimmune pemphigus presenting with diffuse gingival hypertrophy and antibodies against desmocollin 3., PMID:29192983
Routine detection of serum antidesmocollin autoantibodies is only useful in patients with atypical pemphigus., PMID:28815795
Expression of Desmoglein 2, Desmocollin 3 and Plakophilin 2 in Placenta and Bone Marrow-Derived Mesenchymal Stromal Cells., PMID:28154962
Case of pemphigus herpetiformis with immunoglobulin G autoantibodies against desmocollin-3., PMID:27177601
Establishment of IgA ELISAs of mammalian recombinant proteins of human desmocollins 1-3., PMID:27150020
A Case of Pemphigus Herpetiformis with Only Immunoglobulin G Anti-Desmocollin 3 Antibodies., PMID:26848227
Expressions of Thyroid Transcription Factor-1, Napsin A, p40, p63, CK5/6 and Desmocollin-3 in Non-Small Cell Lung Cancer, as Revealed by Imprint Cytology Using a Malinol-Based Cell-Transfer Technique., PMID:26696549
Detection of IgG antibodies to desmoglein 3 and desmocollins 2 and 3 in mucosal dominant-type pemphigus vulgaris with severe pharyngalgia and hyperemia of the bulbar conjunctiva., PMID:26463887
Clinical and immunological findings in 104 cases of paraneoplastic pemphigus., PMID:26358412
Atypical pemphigus with immunoglobulin G autoantibodies against desmoglein 3 and desmocollin 3., PMID:26331291
Anti-desmocollin autoantibodies in nonclassical pemphigus., PMID:25640111
Heterogeneous and abnormal localization of desmosomal proteins in oral intraepithelial neoplasms., PMID:25231147
Human amnion membrane as a substrate for the detection of autoantibodies in pemphigus vulgaris and bullous pemphigoid., PMID:24834757
A case of pemphigus herpetiformis-like atypical pemphigus with IgG anti-desmocollin 3 antibodies., PMID:24807682
p40 is the best marker for diagnosing pulmonary squamous cell carcinoma: comparison with p63, cytokeratin 5/6, desmocollin-3, and sox2., PMID:24805133
Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3., PMID:24635070
IgA/IgG pemphigus with infiltration of neutrophils and eosinophils in an ulcerative colitis patient., PMID:24604005
The expanding spectrum of IgA pemphigus: a case report and review of the literature., PMID:24601812
Two cases of pemphigus vegetans with IgG anti-desmocollin 3 antibodies., PMID:23946009
Regulation and impairments of dynamic desmosome and corneodesmosome remodeling., PMID:23644578
IgA pemphigus with paraneoplastic pemphigus-like clinical features showing IgA antibodies to desmoglein 1/3 and desmocollin 3, and IgG and IgA antibodies to the basement membrane zone., PMID:23517469
Pemphigus vulgaris autoantibody profiling by proteomic technique., PMID:23505434
Recalcitrant pemphigus herpetiformis with high titer of immunoglobulin G antibody to desmoglein 1 and positive IgG antibody to desmocollin 3, elevating thymus and activation-regulated chemokine., PMID:23432082
Atypical pemphigus with exclusively anti-desmocollin 3-specific IgG antibodies., PMID:22735276
Utility of 10 immunohistochemical markers including novel markers (desmocollin-3, glypican 3, S100A2, S100A7, and Sox-2) for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the Lung., PMID:21623236
IgG autoantibodies against desmocollin 3 in pemphigus sera induce loss of keratinocyte adhesion., PMID:21281804
Immunohistochemical subtyping of nonsmall cell lung cancer not otherwise specified in fine-needle aspiration cytology: a retrospective study of 103 cases with surgical correlation., PMID:21246522
Autoimmunity to desmocollin 3 in pemphigus vulgaris., PMID:20952584
Desmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus., PMID:19717567
For research use only. Not for human or drug use.
