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Anti-BECN1 Antibody (R2F44)

Catalog #:   RHG80201 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IP, WB
Accession: Q14457
Overview

Catalog No.

RHG80201

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IP: 1:20, WB: 1:500-1:1000

Target

BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, GT197

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q14457

Applications

IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2F44

Data Image
  • Western blot
    Western blot analysis of Beclin 1 in K562, rat Brain, C6, 3T3, Hela lysates using Beclin 1 antibody.
References

Rituximab-Chidamide combination chemotherapy enhances autophagy to overcome drug resistance in diffuse large B-cell lymphoma., PMID:40258315

Renal Expression Levels of C5a Receptor and Autophagy-related Beclin-1 and LC3A/B Are Simultaneously Enhanced Under Immunoglobulin Treatment in a Rat Model of Sepsis., PMID:40010959

Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity., PMID:39547420

Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267

Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis., PMID:38926151

Does Autophagy have a Role in the Pathogenesis of Pediatric Hepatic Steatosis?, PMID:38809648

VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation., PMID:38360997

The expression of autophagy markers in IVIG-resistant Kawasaki disease and the establishment of prediction model., PMID:38114939

Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185., PMID:38084826

Comparison of the Effects of Recombinant and Native Prolactin on the Proliferation and Apoptosis of Goose Granulosa Cells., PMID:38003565

Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer., PMID:37615625

Autophagy and mitophagy-related extracellular mitochondrial dysfunction of cerebrospinal fluid cells in patients with hemorrhagic moyamoya disease., PMID:37612316

Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice., PMID:37477632

The biomechanistic aspects of renal cortical injury induced by diesel exhaust particles in rats and the renoprotective contribution of quercetin pretreatment: Histological and biochemical study., PMID:34751495

Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1., PMID:34525121

Apelin/APJ signaling activates autophagy to promote human lung adenocarcinoma cell migration., PMID:34186050

Bioactive peptide isolated from sesame seeds inhibits cell proliferation and induces apoptosis and autophagy in leukemic cells., PMID:33907539

Integrated Transcriptomic and Epigenetic Study of PCOS: Impact of Map3k1 and Map1lc3a Promoter Methylation on Autophagy., PMID:33763111

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism., PMID:33749503

Beclin1‑armed oncolytic Vaccinia virus enhances the therapeutic efficacy of R‑CHOP against lymphoma in vitro and in vivo., PMID:33469679

BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293

Abolishing UCHL1's hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice., PMID:33159930

HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death., PMID:33073673

Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545

TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer., PMID:32972302

Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication., PMID:32674313

PKD2/polycystin-2 induces autophagy by forming a complex with BECN1., PMID:32543276

Autophagy coupled to translation is required for long-term memory., PMID:32501746

Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy., PMID:32498399

Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy., PMID:32439945

Treatment of breast cancer with autophagy inhibitory microRNAs carried by AGO2-conjugated nanoparticles., PMID:32345308

The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses., PMID:32249716

EHMT2/G9a Inhibits Aortic Smooth Muscle Cell Death by Suppressing Autophagy Activation., PMID:32174799

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420

Binding of Avibirnavirus VP3 to the PIK3C3-PDPK1 complex inhibits autophagy by activating the AKT-MTOR pathway., PMID:31885313

Disruptions of Autophagy in the Rat Retina with Age During the Development of Age-Related-Macular-Degeneration-like Retinopathy., PMID:31569675

Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts., PMID:31486697

Autophagy precedes apoptosis during degeneration of the Kölliker's organ in the development of rat cochlea., PMID:31189296

Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1-Dependent Manner., PMID:31171562

Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells., PMID:31160892

Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data., PMID:31057298

LC3A, LC3B and Beclin-1 Expression in Gastric Cancer., PMID:30504397

Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation., PMID:30459351

Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer., PMID:30275242

ATG5 is required for B cell polarization and presentation of particulate antigens., PMID:30196744

The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress., PMID:28779098

Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia., PMID:28582465

Autophagy Is an Innate Mechanism Associated with Leprosy Polarization., PMID:28056107

Receptor for advanced glycation end product blockade enhances the chemotherapeutic effect of cisplatin in tongue squamous cell carcinoma by reducing autophagy and modulating the Wnt pathway., PMID:27831944

[Effect of Xinfeng Capsule on AS Patients and Their Serum Immunoglobulin Subtypes and Peripheral Lymphocyte Autophagy]., PMID:27236888

Datasheet

Document Download

Anti-BECN1 Antibody (R2F44).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-BECN1 Antibody (R2F44) [RHG80201]
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