Catalog No.
RHG75801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, WB: 1:1000-1:2000
Target
Transcription factor E2F2, E2F2, E2F-2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14209
Applications
FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2F29
SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma., PMID:38030644
Tumor-Associated Macrophage-Derived Exosomal LINC01232 Induces the Immune Escape in Glioma by Decreasing Surface MHC-I Expression., PMID:37097629
E2f2 Attenuates Apoptosis of Activated T Lymphocytes and Protects from Immune-Mediated Injury through Repression of Fas and FasL., PMID:35008734
Up-Regulated Interleukin-10 Induced by E2F Transcription Factor 2-MicroRNA-17-5p Circuitry in Extrafollicular Effector B Cells Contributes to Autoantibody Production in Systemic Lupus Erythematosus., PMID:34569195
ChIP-sequencing analysis of E2F transcription factor 2 reveals its role in various biological processes of rheumatoid arthritis synovial fibroblasts., PMID:33952803
DNMT1 is associated with cell cycle and DNA replication gene sets in diffuse large B-cell lymphoma., PMID:29137822
Transcription of the Geminin gene is regulated by a negative-feedback loop., PMID:24554762
MicroRNA-let-7a promotes E2F-mediated cell proliferation and NFκB activation in vitro., PMID:24240124
An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus., PMID:21589897
Early patterns of gene expression correlate with the humoral immune response to influenza vaccination in humans., PMID:21357945
The combined effect of BCL-2 over-expression and E2F2 deficiency induces an autoimmune syndrome in non-susceptible mouse strain C57BL/6., PMID:20187704
E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer., PMID:16158053
Chick delta1-crystallin enhancer influences mouse alphaA-crystallin promoter activity in transgenic mice., PMID:15505059
Effect of overexpressing the transcription factor E2F2 on cell cycle progression in rabbit corneal endothelial cells., PMID:15111587
Highly coordinated gene regulation in mouse skeletal muscle regeneration., PMID:12477723
S phase and meristem-specific expression of the tobacco RNR1b gene is mediated by an E2F element located in the 5' leader sequence., PMID:11884409
Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity., PMID:11754817
5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients., PMID:11300326
The chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements., PMID:11279041
Expression patterns of retinoblastoma and E2F family proteins during corneal development., PMID:10752941
BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases., PMID:9244350
Accumulation of E2F-4.DP-1 DNA binding complexes correlates with induction of dhfr gene expression during the G1 to S phase transition., PMID:9020173
E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry., PMID:8657117
Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression., PMID:8622649
Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F., PMID:8246995