Catalog No.
RHG68001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
PEBP2-beta, Core-binding factor subunit beta, CBF-beta, CBFB, SL3/AKV core-binding factor beta subunit, Polyomavirus enhancer-binding protein 2 beta subunit, PEA2-beta, SL3-3 enhancer factor 1 subunit beta
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13951
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2F11
Emerging therapies for inv(16) AML., PMID:33821975
Detection of selection signatures for response to Aleutian mink disease virus infection in American mink., PMID:33536540
Clinical and immunological features of platelet transfusion refractoriness in young patients with de novo acute myeloid leukemia., PMID:32419364
The Incidence and Immunophenotypic and Genetic Features of JL1 Expressing Cells and the Therapeutic Potential of an Anti-JL1 Antibody in De Novo Pediatric Acute Leukemias., PMID:30809981
Charged Amino Acid-rich Leucine Zipper-1 (Crlz-1) as a Target of Wnt Signaling Pathway Controls Pre-B Cell Proliferation by Affecting Runx/CBFβ-targeted VpreB and λ5 Genes., PMID:27226553
Detection of fusion genes at the protein level in leukemia patients via the flow cytometric immunobead assay., PMID:21123134
Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells., PMID:19800266
Crlz1 activates transcription by mobilizing cytoplasmic CBFbeta into the nucleus., PMID:19735751
Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia with inv(16)(p13q22) as a sole genetic abnormality., PMID:17452259
Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22)., PMID:17063086
An inv(16)(p13q22) positive acute myeloid leukaemia relapsing as acute precursor B-cell lymphoblastic leukaemia., PMID:15339697
PEBP2 and c-myb sites crucial for lambda5 core enhancer activity in pre-B cells., PMID:11745333
Minimally differentiated acute myeloid leukemia (AML M0): clinico-biological findings of 29 cases., PMID:10721774
The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains., PMID:10545320
The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates., PMID:9819429
Characterization and use of an antibody detecting the CBFbeta-SMMHC fusion protein in inv(16)/t(16;16)-associated acute myeloid leukemias., PMID:9490670
Differentiation dependent expression and distinct subcellular localization of the protooncogene product, PEBP2beta/CBFbeta, in muscle development., PMID:9191054
Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells., PMID:8818654
For research use only. Not for human or drug use.
