Catalog No.
RHG61801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
53BP2, Renal carcinoma antigen NY-REN-51, Bcl2-binding protein, TP53BP2, Bbp, Tumor suppressor p53-binding protein 2, p53BP2, BBP, ASPP2, Apoptosis-stimulating of p53 protein 2, p53-binding protein 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13625
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2E87
ASPP2 suppression promotes malignancy via LSR and YAP in human endometrial cancer., PMID:32266459
Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia., PMID:30952616
Amphiregulin impairs apoptosis-stimulating protein 2 of p53 overexpression-induced apoptosis in hepatoma cells., PMID:28351301
ASPP2 suppresses stem cell-like characteristics and chemoresistance by inhibiting the Src/FAK/Snail axis in hepatocellular carcinoma., PMID:27473084
Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis., PMID:24920620
Cell type specific expression of the apoptosis stimulating protein (ASPP-2) in human tissues., PMID:21183427
The DEAD box protein Ddx42p modulates the function of ASPP2, a stimulator of apoptosis., PMID:19377511
Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis., PMID:14985081
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human., PMID:12524540
Apoptotic and proliferative markers in chordomas: a study of 26 tumors., PMID:12170453
Biologic factors and response to radiotherapy in carcinoma of the cervix., PMID:11437923
Characterization of the subventricular zone of the adult human brain: evidence for the involvement of Bcl-2., PMID:10802345
Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2., PMID:9748285
Radioresistance and p53 status of T2 laryngeal carcinoma. Analysis by immunohistochemistry and denaturing gradient gel electrophoresis., PMID:8780536
For research use only. Not for human or drug use.
