Catalog No.
RHG47001
Species reactivity
Human, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IP: 1:20, WB: 1:500-1:1000
Target
ATP-dependent DNA helicase VIII, hDH VIII, G3BP-1, G3BP, G3BP1, Ras GTPase-activating protein-binding protein 1, GAP SH3 domain-binding protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13283
Applications
IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2E19
Revealing Stress Granule Compositional Heterogeneity through Antibody-Guided Proximity Labeling., PMID:40198209
On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469., PMID:40156465
Nanobody-assisted nanoluciferase fragment complementation for in situ measurement and visualization of endogenous protein-protein interaction., PMID:39752888
Stress granules formation in HEI-OC1 auditory cells and in H4 human neuroglioma cells secondary to cisplatin exposure., PMID:39575153
Lin28a forms an RNA-binding complex with Igf2bp3 to regulate m6A-modified stress response genes in stress granules of muscle stem cells., PMID:39021312
Porcine epidemic diarrhea virus E protein induces formation of stress granules and attenuates protein translation through activation of the PERK/eIF2α signaling pathway., PMID:38643723
Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing., PMID:38200227
Synergistic anti-infectious bronchitis virus activity of Phillygenin combined Baicalin by modulating respiratory microbiota and improving metabolic disorders., PMID:38150830
G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer., PMID:38084438
Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS., PMID:37071594
Development of a novel light-up probe for detection of G-quadruplexes in stress granules., PMID:35902691
Bruton's tyrosine kinase phosphorylates scaffolding and RNA-binding protein G3BP1 to induce stress granule aggregation during host sensing of foreign ribonucleic acids., PMID:35798143
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway., PMID:34614429
Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation., PMID:32992901
Disruption of galectin-3 and galectin-3 binding protein (G3BP) interaction by dietary pectic polysaccharides (DPP) - Arrest of metastasis, inhibition of proliferation and induction of apoptosis., PMID:31356934
Pseudophosphatase MK-STYX Alters Histone Deacetylase 6 Cytoplasmic Localization, Decreases Its Phosphorylation, and Increases Detyrosination of Tubulin., PMID:30909412
Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories., PMID:27749929
Simultaneous detection of the subcellular localization of RNAs and proteins in cultured cells by combined multicolor RNA-FISH and IF., PMID:27664292
A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies., PMID:26875185
Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway., PMID:25962958
Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication., PMID:25653451
UVC-induced stress granules in mammalian cells., PMID:25409157
In vitro methylation assay to study protein arginine methylation., PMID:25350748
Production of a dominant-negative fragment due to G3BP1 cleavage contributes to the disruption of mitochondria-associated protective stress granules during CVB3 infection., PMID:24260247
Targeting cancer with a bi-functional peptide: in vitro and in vivo results., PMID:23812212
Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP., PMID:23092511
Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility., PMID:16973615
[Monoclonal antibody against G3BP: preparation, characterization and its application in analysis of human tumors]., PMID:16091175
Vaccinia virus intermediate stage transcription is complemented by Ras-GTPase-activating protein SH3 domain-binding protein (G3BP) and cytoplasmic activation/proliferation-associated protein (p137) individually or as a heterodimer., PMID:15471883
Association of rasGAPSH3 binding protein 1, G3BP1, and rasGap120 with integrin containing complexes induced by an adhesion blocking antibody., PMID:15253432
Galectin 3 and its binding protein in rheumatoid arthritis., PMID:14558084
The expression of Ras-GTPase activating protein SH3 domain-binding proteins, G3BPs, in human breast cancers., PMID:12587999
Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors., PMID:11888885
IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2., PMID:10969074
For research use only. Not for human or drug use.
