Catalog No.
YHC86601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln133-Gly337
Predicted molecular weight
25.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11215
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, ITGAM, CD11b, CD11 antigen-like family member B, Integrin alpha-M, CR3A, CD11B, Neutrophil adherence receptor
Hepatocyte necroptosis is associated with liver damage in dairy cows with ketosis., PMID:40513868
CD11b as a diagnostic biomarker of rheumatoid arthritis and as a risk factor of periodontitis: a pilot study., PMID:40512337
Adoptive Transfer of Lepr+ Bone Marrow Cells Attenuates the Osteopetrotic Phenotype of db/db Mice., PMID:40507931
Exploring the role of neutrophils in inflammatory pain hypersensitivity via single-cell transcriptome profiling., PMID:40503232
Increased Fascin1 and Pak1 Expressions Enhance Age-Associated B-Cell Actin Cytoskeleton Remodeling and Motility., PMID:40500987
CD154:CD11b blockade enhances CD8+ T cell differentiation during infection but not transplantation., PMID:40485581
Caspase-8-driven NLRP3 inflammasome activation exacerbates bronchopulmonary dysplasia by increasing the apoptosis and pyroptosis crosstalk of alveolar epithelial cells., PMID:40483833
Trem2 regulates microglial migratory responses via type I interferon signaling during photoreceptor degeneration., PMID:40468324
Transglutaminase 2-expressing macrophages modulate adipose tissue inflammation., PMID:40467990
Cell-specific protein expression in Alzheimer's disease prefrontal cortex., PMID:40465637
HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages., PMID:40453963
Developing and Characterizing the Tumor-Targeting Efficiency of an Anti-EphA2-CD11b Bispecific Antibody., PMID:40434019
Eugenol Alleviates Cerebral Ischemia-Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up-Regulating Tripartite Motif Protein 59., PMID:40432346
Mapping Inherited Genetic Variation with Opposite Effects on Autoimmune Disease and Four Cancer Types Identifies Candidate Drug Targets Associated with the Anti-Tumor Immune Response., PMID:40428397
Qing-Fei-Pai-Du-Tang ameliorates lipopolysaccharide-induced rat acute lung injury through attenuating pulmonary microcirculatory disturbances via multi-target regulation., PMID:40412059
Mammary leukocytes function of endotoxin tolerant goat induced by intrauterine infusion of lipopolysaccharide., PMID:40405625
Inhibition of Alternative and Terminal Complement Pathway Components Modulate the Immune Response Against Bacteria and Fungi in Whole Blood., PMID:40387159
Mechanism of Shuangyang Houbitong granules against acute erythroleukemia through PI3K/AKT and JAK/STAT signaling pathways., PMID:40381820
Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells., PMID:40381622
Interleukin-7 enhances recruitment of MDSCs by regulating MCP-1 via JAK1/STAT3 signaling pathway in non-small cell lung cancer., PMID:40374882
Targeting GPR84 to alleviate acute immune-mediated liver injury., PMID:40369402
GATA1-mediated Notch signaling augment antitumor immunity of CD11b+CD27- natural killer cells maturation via BCL9/β-catenin signal., PMID:40366806
Sensitivity of Various Indicators in a Mouse Sensitive Skin Model Treatment with 4-tert-Butylcyclohexanol and Pimecrolimus., PMID:40362313
The Effect of GB1 on DSS-Induced Colitis in WT and Nlrp3-/- Mice., PMID:40362256
[Mechanism of icariin in promoting osteogenic differentiation of BMSCs and improving bone metabolism disorders through caveolin-1/Hippo signaling pathway]., PMID:40350837
Dual-action membrane-chimeric liposomes with self-reinforcing targeting for acute lung injury treatment., PMID:40349780
Synergistic effects of the Aβ/fibrinogen complex on synaptotoxicity, neuroinflammation, and blood-brain barrier damage in Alzheimer's disease models., PMID:40344319
Knockdown of dual-specificity phosphatase 3 drives differentiation and polarization of myeloid leukemia cells into macrophages with reduced proliferative and DNA repair fitness., PMID:40334397
Tartaric Acid Exacerbates DSS-Induced Colitis by Promoting Eosinophilic Inflammation via IL-13 and IL-5Rα Upregulation., PMID:40333150
Single-cell RNA sequencing and spatial transcriptomics reveal unique subpopulations of infiltrating macrophages and dendritic cells following AKI., PMID:40331777
The up-regulation of TGF-β1 by miRNA-132-3p/WT1 is involved in inducing leukemia cells to differentiate into macrophages., PMID:40327646
Effect of calcitriol on myeloid-derived suppressor cells in physiological aging., PMID:40316223
Dendritic cell expression of MyD88 is required for rotavirus-induced B cell activation., PMID:40304491
Combination of growth hormone receptor antagonist and radiation reduces tumour growth in a lung cancer xenograft model., PMID:40298337
The synergistic antitumor effect of Karanahan technology and in situ vaccination using anti-OX40 antibodies., PMID:40296901
Elevated PD-L1 Expression on Circulating Classical Monocytes Upon Checkpoint Inhibitor Therapy Is Associated With Increased Plasma Interleukin 5 in Patients With Lung Cancer., PMID:40295054
Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis., PMID:40270956
[Inhibition of osteogenic differentiation of mouse bone marrow mesenchymal stem cells and maxillary expansion osteogenesis by cytoskeleton-associated protein 4 knockout]., PMID:40268538
RANKL promotes MT2 degradation and ROS production in osteoclast precursors through Beclin1-dependent autophagy., PMID:40267773
Helminth reshapes host gut microbiota and immunoregulation by deploying an antimicrobial program of innate immunity., PMID:40266093
Immunophenotypic Profiling of Acute Promyelocytic Leukemia: Insights From a Large Cohort., PMID:40251942
Sex-Specific Anti-Inflammatory Effects of a Ketogenic Diet in a Mouse Model of Allergic Airway Inflammation., PMID:40243683
The Role of Neutrophil CD11b Compared to Neutrophil CD64 as an Early Diagnostic, Monitoring, and Prognostic Sepsis Marker in Neonatal ICUs: Case-Control-Methodological Study., PMID:40224545
Necrostatin-1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice., PMID:40222051
The transition between M1 and M2 macrophage phenotypes is associated with the disease status following CD19 CAR-T therapy for B cell lymphoma/leukemia., PMID:40216772
Association between immune cells and allergic purpura: a Mendelian randomization study., PMID:40211366
IRF4-regulated transcriptional and functional heterogeneity of lung-resident CD11b+ cDC2 subsets during influenza virus infection., PMID:40209091
BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammation., PMID:40195021
Generation and characterization of 7DC-DM1: a non-cleavable CD47-targeting antibody-drug conjugates with antitumor effects., PMID:40187444
Mindin orchestrates the macrophage-mediated resolution of liver fibrosis in mice., PMID:40186763
For research use only. Not for human or drug use.
