Catalog No.
RHG34701
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20, WB: 1:500-1:1000
Target
FKHL7, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FREAC3, FREAC-3, FOXC1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q12948
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D59
Silencing of forkhead box C1 reduces nasal epithelial barrier damage in mice with allergic rhinitis via epigenetically upregulating secreted frizzled-related protein 5., PMID:38422887
Isorhynchophylline exerts anti-asthma effects in mice by inhibiting the proliferation of airway smooth muscle cells: The involvement of miR-200a-mediated FOXC1/NF-κB pathway., PMID:31733831
Directed Differentiation of Human Corneal Endothelial Cells From Human Embryonic Stem Cells by Using Cell-Conditioned Culture Media., PMID:30025120
Forkhead box C1 gene variant causing glaucoma and small vessel angiopathy can mimic multiple sclerosis., PMID:29751260
Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation., PMID:27907090
Foxc1 Ablated Mice Are Anhidrotic and Recapitulate Features of Human Miliaria Sweat Retention Disorder., PMID:27592801
Targeted overexpression of TGF-α in the corneal epithelium of adult transgenic mice induces changes in anterior segment morphology and activates noncanonical Wnt signaling., PMID:23412089
FOXC1 contributes to microvascular invasion in primary hepatocellular carcinoma via regulating epithelial-mesenchymal transition., PMID:22991501
Derivation of corneal endothelial cell-like cells from rat neural crest cells in vitro., PMID:22860120
Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2., PMID:22493429
Canonical Wnt signaling regulates Foxc1/2 expression in P19 cells., PMID:19782461
SOX15 and SOX7 differentially regulate the myogenic program in P19 cells., PMID:19489079
FoxC1 is essential for vascular basement membrane integrity and hyaloid vessel morphogenesis., PMID:19458328
Severe molecular defects of a novel FOXC1 W152G mutation result in aniridia., PMID:19279310
Human p32 is a novel FOXC1-interacting protein that regulates FOXC1 transcriptional activity in ocular cells., PMID:18676636
The establishment of a predictive mutational model of the forkhead domain through the analyses of FOXC2 missense mutations identified in patients with hereditary lymphedema with distichiasis., PMID:16081467
Identification of target genes regulated by FOXC1 using nickel agarose-based chromatin enrichment., PMID:15505035
The wing 2 region of the FOXC1 forkhead domain is necessary for normal DNA-binding and transactivation functions., PMID:15277473
Identification and analysis of a novel mutation in the FOXC1 forkhead domain., PMID:14578375
FOXC1 transcriptional regulation is mediated by N- and C-terminal activation domains and contains a phosphorylated transcriptional inhibitory domain., PMID:11782474
The forkhead/winged-helix gene, Mf1, is necessary for the normal development of the cornea and formation of the anterior chamber in the mouse eye., PMID:10395790
For research use only. Not for human or drug use.
